Previous issue | Volume 94 | ESPE2021

59th Annual ESPE (ESPE 2021 Online)

Online,
22 Sep 2021 - 26 Sep 2021

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The 59th ESPE Annual Meeting will now be held online in September 2021.

Working Group Symposia

ESPE Working Group on Bone and Growth Plate (BGP) Symposium

hrp0094wg1.2 | ESPE Working Group on Bone and Growth Plate (BGP) Symposium | ESPE2021

Craniosynostoses - genes and bone biology

Twigg Steve ,

Expansion of the skull vault to accommodate the growing brain is driven primarily by growth at cranial sutures. These are fibrous joints between the flat bones of the skull that translate growth pressure from the brain into a balanced proliferation and differentiation of cells of the osteoblast lineage. This process is sensitive to environmental and genetic insults and premature fusion of one or more sutures, termed craniosynostosis is a common (~1 in 2000), and serious cranio...