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59th Annual ESPE (ESPE 2021 Online)

Online,
22 Sep 2021 - 26 Sep 2021

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The 59th ESPE Annual Meeting will now be held online in September 2021.

Working Group Symposia

ESPE Working Group on Disorders of Sex Development (DSD) Symposium

hrp0094wg4.1 | ESPE Working Group on Disorders of Sex Development (DSD) Symposium | ESPE2021

New insights into sex differentiation and their relevance to disorders of sex development

Nicol Barbara ,

Embryos initially form undifferentiated gonads, reproductive tracts and external genitalia that will progressively acquire female or male characteristics. This fate decision is initiated in the undifferentiated gonads and depends on sex chromosomes and fine-tuned expression of complex networks of molecular pathways. Defects at different levels of this cascade of events can trigger a large spectrum of Disorders of sex development (DSDs), defined as “congenital conditions w...

hrp0094wg4.2 | ESPE Working Group on Disorders of Sex Development (DSD) Symposium | ESPE2021

Advances in the Measurement of Steroid Hormones

Wudy Stefan A. ,

While steroid hormones as universal signals of intercellular communication arose very early in the evolution of life, it was only recently that their isolation and structural elucidation has been achieved. Steroid hormones are small, structurally closely related molecules sharing the typical 4-cyclic sterane basic structure. However, there is a big diversity of functionally different steroid hormones and their metabolism is complex. Thus, their analysis is highly challenging. ...