ESPE Abstracts

Methods: A retrospective analysis of children with T1DM attending the Paediatric-diabetes service in an inner-city hospital. We included CYPD with paired values of hospital-measured BMI and HbA1C during 2 periods covering pre and post-lockdown (January-June 2020 versus November2020-April 2021). Children without paired values were excluded. HbA1C is expressed in DCCT% units. BMI calculated in absolute values, given the short study period.

Results: 49 children with T1DM were included (55% male and 45% female, mean age of 12.86 years (range 4-18 years). The mean duration of diabetes was 6.39 ± 3.13 years. 21/49 (42.8%) patients had an increase of HbA1c > 0.5% (range 0.5- 3.7%) whilst 8/49(16%) patients showed an improvement in HbA1c >0.5%(range 0.5-2.4%).There was a non-significant trend to higher HbA1C in the second period compared to the first (8.74±1.76 vs 8.53±1.91; mean-difference 0.02?±1.29; P = 0.27). Patients who had a decrease in their mean HbA1c had better control prior to lockdown (8.86% vs 10.66% (P = 0.004)).The mean change in BMI was +1.21kg/sqm (range -2.9 to 9.0 kg/sqm) in absolute values, with a pre-lockdown mean BMI of 19.90 ±4.39 kg/sqm versus 21.11 ±5.10 kg/sqm in the post lockdown period.

References: Cognigni M et al. HbA1c and BMI after lockdown for COVID?19 in children and adolescents with type 1 diabetes mellitus. Acta Paediatrica VermaA, et al. Impact of lockdown in COVID 19 on glycemic control in patients with type 1 Diabetes Mellitus. Clinical Research & Reviews, 14(5), 1213-1216.