Diabetes and Insulin

Introduction: Diabetes mellitus can develop as a result different etiology. Mitochondrial diseases may also cause diabetes mellitus. However, mitochondrial mutations are generally thought to be accompanied by a severe clinical finding. We present a patient who is determined 80% heteroplasmic deletion in the MT-DNT1 gene, with hearing loss and mitochondrial diabetes, which is quite different from the classical phenotype.Case:</str...

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hrp0095p2-50 | Diabetes and Insulin | ESPE2022

Inhaled glucagon, a new well-accepted therapeutic tool in pediatrics

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , José Espina-Diez Maria

On 01/14/2021, the European Commission authorized the marketing of Baqsimi® 3 mg (nasal glucagon), a powder medicine, ready to be used, in the treatment of severe hypoglycemia in adults, adolescents and children over four years of age with diabetes mellitus. Baqsimi® is the first and only nasal glucagon treatment available approved in the European Union (EU), and has been designed as a rescue treatment in cases of severe hypoglycemia, being absorbed passively into the ...

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hrp0095p2-51 | Diabetes and Insulin | ESPE2022

Effect of combined hormonal contraceptives use in telomere length and metabolic profile in young women with T1D

Giraudo Franco , Lardone Cecilia , Castro Andrea , López Patricia , Iñiguez Germán , Merino Paulina , Salinas Abril , Cassorla Fernando , Codner Ethel

Introduction: The metabolic effects of oral hormonal contraception (OC) on telomere length (RTL) in young women with T1D are unknown.Objective: To determine the effect of using an OC on glycemic control, inflammatory profile, and RTL in young women with T1D and healthy women without diabetes (C).Methodology: T1D (n:20, age: 20.6 &pm; 3.3 years) and C (n:22, age 20.2 &pm; 3 years) u...

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hrp0095p2-52 | Diabetes and Insulin | ESPE2022

Bone and mineral turnover in newly diagnosed children and adolescents with type 1 diabetes mellitus

Slavcheva-Prodanova Olga , Savova Radka , Archinkova Margarita , Konstantinova Maia

Introduction: There is still controversy about the levels of bone turnover markers at type 1 diabetes (T1D) onset and their dynamics at follow-up. Bonfanti et al. did not find any differences at onset, while few months afterwards beta cross laps level was significantly lower. Pater et al. found lower levels of osteocalcin and Log beta cross laps at onset which normalized after 3 and 12 months. Possible mechanisms are metabolic acidosis, decre...

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hrp0095p2-53 | Diabetes and Insulin | ESPE2022

Clinical and immunological characteristics of new-onset type 1 diabetes in children during the COVID-19 pandemic

Gil Margolis Merav , Weizman Sarit , Lazar Liora , Yakobovich-Gavan Michal , Tenenbaum Ariel , Phillip Moshe , Oron Tal

Background: Type 1 Diabetes (T1D) is a chronic disease resulting from autoimmune destruction of insulin-secreting pancreatic β cells. Viruses are known to play a role in the pathogenesis of T1D. There is no consistent evidence that SARS-CoV-2 induces T1D in children or adults. Nevertheless, evidence suggests that the SARS-CoV-2 affects β cell function, suggesting a role for the virus in the pathogenesis of the disease. It is thus plausible that the e...

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hrp0095p2-54 | Diabetes and Insulin | ESPE2022

Abstract Withdrawn...

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hrp0095p2-55 | Diabetes and Insulin | ESPE2022

A case of de novo ABCC8 gene mutation resulting in Transient Neonatal Diabetes

Clemente Marisa Ferreira

Neonatal diabetes is characterised by hyperglycaemia in the first 6 months of life. Transient neonatal diabetes (TND) is differentiated from permanent neonatal diabetes by its remission in infancy/early childhood, with possible relapse during adolescence in 50% of the cases. Incidence of neonatal diabetes is thought to range from 1:90,000 to 1:160,000. A gene mutation affecting pancreatic beta cells synthesis/secretion of insulin is present in more than 80% of the cases. Overe...

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hrp0095p2-56 | Diabetes and Insulin | ESPE2022

Monogenic Diabetes (MODY) in Adolescents and Personalized Treatment.

Xu Xu , Volcotrub Egor , Ten Svetlana

Background: MODY can be mistaken for Diabetes type 1 or type 2.Objective: To evaluate genetic background in 22 patients presented with diabetes, negative islet cell antibodies, normal C-peptide and positive family history of diabetes. Genetic testing was done at Invitae laboratory and evaluated 28 genes for diagnosis of MODY.Results: Patients were divided into 2 groups: Group 1 wit...

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hrp0095p2-57 | Diabetes and Insulin | ESPE2022

Outcome of positive adrenal antibodies identified on screening in children with T1DM

Pinsker Jonathan , McNeilly Jane , Whyte Karen , Kuehne Vaiva , Faisal Ahmed S , Guftar Shaikh M

Background: Primary adrenal insufficiency (PAI) is characterised by the immune destruction of the adrenal cortex and leads to impaired production of the adrenal hormones. It is a potentially life-threatening condition that can be managed if identified early. The onset is insidious and often difficult to diagnose. Screening for adrenal autoantibodies is routinely performed in autoimmune conditions such as type 1 diabetes mellitus (T1DM). The guidance around the...

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hrp0095p2-58 | Diabetes and Insulin | ESPE2022

Real-world use of continuous glucose monitoring and its effect on glycemic control among Korean children, adolescents, and young adults with type 1 diabetes

Lee Dahye , Choe Yunsoo , Jeong Lee Yun , Ho Shin Choong , Ah Lee Young

Background: The Korean National Health Insurance Service has started reimbursing the cost of continuous glucose monitoring (CGM) in type 1 diabetes (T1D) in 2019. We investigated the effect of CGM use on glycemic control among Korean children, adolescents, and young adults with T1D in a real-world setting.Method: We retrospectively reviewed the medical records of childhood-onset T1D patients aged < 30 years (n</em...

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hrp0095p2-59 | Diabetes and Insulin | ESPE2022

First case of Diabetes Mellitus Caused by compound heterozygous changes in the WFS1 and PTF1A Genes from Kazakhstan

Aralbayeva Dariga , Bolatbek Kassiyet , Berikkan Aigerim , Ten Svetlana , Bhangoo Amrit , Nurbekova Akmaral

Background: We report the first case of Wolfram syndrome with heterozygous polymorphisms of WFS1 and PTF1A genes.Case description: 16 years-old girl presented with diabetes mellitus at 12 years of age with HbA1c of 8.4 %. The IA-2, Islet cell, Insulin antibodies (Ab) were negative. GAD Ab were positive 26 U/ml (nl< 4). C-peptide level was normal 1.33 ng/ml (1.1-4.4 ng/ml) even after 4 years of diagnosis. She was initi...

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hrp0095p2-60 | Diabetes and Insulin | ESPE2022

Pediatric Diabetic Ketoacidosis with Hyperosmolarity in Korea: Clinical implications and Outcomes

Kang Jaebeen , Yoo Sukdong , Young Yoon Ju , Kun Cheon Chong

Objectives: Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are potential life-threatening emergencies of diabetes mellitus (DM). DKA and HHS may coexist, making the treatment difficult. With increasing rates of childhood obesity and pediatric type 2 DM, cases of mixed HHS and DKA are expected to occur more frequently than before. But the frequency and implications of combined DKA/HHS in children/adolescents are not yet well known. We ai...

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hrp0095p2-61 | Diabetes and Insulin | ESPE2022

Ketoacidosis and Age Distribution in New-Onset Type 1 Diabetes During Covid-19 Pandemic

Vinkovic Maja , Krnic Nevena , Bogdanic Ana , Dumic Kubat Katja , Braovac Duje , Spehar Uroic Anita

Background:There are numerous reports indicating increased risk of diabetic ketoacidosis (DKA) in new-onset type 1 diabetes (T1D) in childhood during COVID-19 pandemic. Delayed diagnosis, reduced access to immediate health care and psychological effects of pandemic have been suggested as possible reasons.Methods: We conducted cross sectional, single-center study at Department of Pediatrics, University Hospital Center Zag...

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hrp0095p2-62 | Diabetes and Insulin | ESPE2022

Time Trend and Potential Risk Factors for Celiac Disease Development in Children with Type 1 Diabetes Mellitus-10-year Single Center experience

Ahmed Fatima , Al Jneibi Sara , Rajah Jaishen , Chedid Krystel , Al Remeithi Sareea

Background: Celiac disease (CD) is an important association with type 1 diabetes (T1DM) with a significant impact on growth and glycaemic control. The frequency of coexistence of T1DM and CD is widely described, ranging from 2.5 to 16.4% in 23 studies worldwide, much greater than the general population risk of 1%. The risk of CD is higher among younger children (less than 4 years), females and during the first few years of T1DM diagnosis. Objectives: We aimed ...

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hrp0095p2-63 | Diabetes and Insulin | ESPE2022

Atypical diabetes with spontaneous remission associated with systemic lupus erythematosus in an adolescent girl with African ancestry

Luterbacher Fanny , Schwitzgebel Valerie

Background: New-onset diabetes in youth can classically fall into three categories: type 1 diabetes (T1D), type 2 diabetes (T2D), or monogenic diabetes (MD). This classification is based on the underlying disease mechanisms, dictates treatment, and predicts outcome. Type B insulin resistance syndrome (TBIR) and ketosis-prone diabetes (KPD) are described in the African population, but their incidence in the pediatric population is very low.<p class="abstext...

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hrp0095p2-64 | Diabetes and Insulin | ESPE2022

Diabetes Secondary to Glucokinase Gene Polymorphism with Obesity and Fluctuating Severity of Diabetes

Aljalily Sarraa , Xu Xu , Ten Svetlana

Case report: 14 yrs. old Hispanic girl was referred for evaluation of diabetes (Hb A1c 9.8 %) and morbid obesity BMI 36 kg/m2. She developed acanthosis nigricans, elevated triglycerides (TG) 1162 mg/dl, low HDL 34 mg/dl, fatty liver with elevated AST 84 U/l, ALT 103 U/L. The abdominal sonogram revealed significant hepatomegaly with moderate steatosis. Her islet cell AB were negative, C-peptide 3.11 ng/ml was normal. She has a strong family history of diabetes:...

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hrp0095p2-65 | Diabetes and Insulin | ESPE2022

Effect of carbohydrate counting education in Korean patients with type 1 diabetes.

In Lee Hae , Kwon Ahreum , Suh Junghwan , Lee Myeongseob , Song Kyungchul , Wook Chae Hyun , Kim Ho-Seong

Background: The achievement and maintenance of normoglycemia is one of the most important goals to prevent both short and long-term complications in type 1 diabetes mellitus (T1DM). As carbohydrate acts as the primary macronutrient affecting postprandial glycemic response, carbohydrate counting is crucial in adjusting prandial insulin doses to preserve postprandial blood glucose within normal limits. The purpose of this study is to examine the effect for carbo...

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hrp0095p2-66 | Diabetes and Insulin | ESPE2022

A Novel Mutation in the Hepatocyte Nuclear Factor 1-Alpha Detected in Case of a 13-Year-Old Female with Maturity Onset Diabetes of the Young (MODY)

Hyang Cho Ja , Woon Jung Hae , Shik Shim Kye

Maturity onset diabetes of the young (MODY) is a rare type of non-autoimmune diabetes mellitus which usually present in young adulthood. An estimated prevalence was 1.2% within the pediatric diabetic population. To date it has been proposed that pathogenic variants in at least 14 genes cause MODY. Among these genes, most cases result from mutations in HNF1A (MODY3), GCK (MODY2), HNF4A (MODY1) and HNF1B (MODY5). The patient is a 13-year-old, previously healthy, nonobese female ...

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hrp0095p2-67 | Diabetes and Insulin | ESPE2022

Impact on metabolic control in pediatric patients with use of technology applied to type 1 diabetes

Gil Poch Estela , Babiano Benito Lucía , Javier Arroyo Díez Francisco

Background and Aims: The treatment of type 1 diabetes (T1D) requires a great involvement of the patient to achieve optimal blood glucose levels. Technological devices have been developed for individualized treatment, fewer interventions of the patient, and evidence of improved metabolic control. The aim of the study is to know data on metabolic control in a group of pediatric patients with T1D treated with new technologies, compared to patients treated with mu...

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hrp0095p2-68 | Diabetes and Insulin | ESPE2022

Diabetic Ketoacidosis Resulting From I-port Device Failure In Multiple Cases

Lawal Kaltumi , Hall Nikki , Mathew Verghese , Gupta anjay

Background: Multiple daily injections of insulin for children and young people with diabetes can be very daunting and, some have a phobia of needles. As a result, for some individuals, the use of an i-port device can be life-changing and help with their diabetes management. The i-port is an injection port that enables diabetes patients to administer their insulin without having to puncture their skin multiple times in a day. In most cases, the i-port can stay ...

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hrp0095p2-69 | Diabetes and Insulin | ESPE2022

Impact of β-cell function and glucose effectiveness on the development of type 2 diabetes mellitus in obese European children and adolescents

Ellen Kratzer Sophie , Vogt Josef , Kohlsdorf Katja , von Schnurbein Julia , Wabitsch Martin , Denzer Christian

Objectives: Despite high prevalence rates of childhood obesity, youth-onset T2DM occurs in a comparably lower incidence in Europe than in other world regions. Available data from cohorts of obese children and adolescents living in the US suggest a parallel decline of insulin sensitivity and β-cell function as key factors in the pathophysiology of early-onset T2DM. If these results can be applied to European children and adolescents is currently unknown.</...

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hrp0095p2-70 | Diabetes and Insulin | ESPE2022

Familial Genetic Syndrome of Severe Insulin Resistance and Hyperandrogenemia in a young girl with Polycystic Ovary Morphology

Patriciu Zubascu Gheorghita , Florina Predescu Andrada , Maria Stancu Ana , Tarna Mihaela , Nicoleta Cima Luminita , Alnuaimi Osama , Tincuta Petca Aida , Plaiasu Vasilica , Fica Simona , plate and mineral metabolism growth

Introduction: Signs of hyperandrogenemia are common through adolescent and young females, hirsutism affecting 5% of reproductive -aged women. The most common cause of hyperandrogenemia and insulin resistance (IR) is polycystic ovary syndrome (PCOS) (1). The differential diagnosis includes congenital adrenal hyperplasia (CAH) (2), androgen secreting tumors, but also very rare genetic syndromes of IR.Case report: A 13 year...

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hrp0095p2-71 | Diabetes and Insulin | ESPE2022

The Effect of Parental Monitoring on Glycemic Control in Adolescents with Type 1 Diabetes

Can Yılmaz Gülay , Nur Peltek Kendirci Havva

Introduction and Aim: Adolescence is the period when the management and metabolic control of the disease are the most difficult in type 1 diabetes mellitus, and the adolescent and parents experience the most intense problems. Although there are studies showing that parental support positively affects glycemic control and treatment compliance, studies investigating the effect of parental monitoring on glycemic control are limited. In this study, it was aimed to...

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hrp0095p2-72 | Diabetes and Insulin | ESPE2022

A rare case of Type 1 Diabetes preceded by Hashimoto thyroiditis and followed by Multiple Sclerosis

Karabouta Zacharoula , Bisbinas Vasiliki , Evangeliou Athanasios

Introduction: Type 1 Diabetes(T1) and autoimmune thyroid disease(AITD) can occur concomitantly. Multiple sclerosis(MS), a chronic condition resulting from dysfunction of the immune system, may co-occur with T1D.Aim: We present a 17-year-old boy presented with AITD at 10y old and within seven years developed T1D and MS.Subjects and methods: The patient presented at the age of 10y ol...

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hrp0095p2-73 | Diabetes and Insulin | ESPE2022

Recurrent glycogenic hepatopathy in an 11-year-old boy with poor glycemic controlled type 1 diabetes mellitus

Sasaoka Daiki , Kojima Kanako , Koga Nobuhiko , Sasaki Fusako , Tanaka Yukari , Yatsuga Shuichi , Nagamitsu Shinichiro

Introduction: Glycogenic hepatopathy (GH) is a rare diabetic complication that induces hepatomegaly and elevated transaminases, which can often appear in type 1 diabetes mellitus (T1DM) with poor glycemic control. GH appears when excess glycogen accumulates in the liver through continued hyperglycemia with intensive insulin therapy. We show a pediatric case of recurrent GH due to poor glucose controlled with complicated family environment and mildly intellectu...

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hrp0095p2-74 | Diabetes and Insulin | ESPE2022

Knowledge and Confidence of Omani Paediatric Residents in Managing Diabetic Ketoacidosis (DKA); A Cross Sectional Survey

Al-Rawahi Maryam , Alsaffar Hussain

Background: Diabetic ketoacidosis is a common complication of Type 1 diabetes Mellitus (T1DM). Unfortunately, medical errors are not uncommon during management of DKA leading to significant morbidity and mortality. Junior doctors/residents are usually the clinicians who initiate the management of DKA. There are many studies conducted to assess the knowledge of junior doctors, residents, and medical students in management of DKA in many countries including Bahr...

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hrp0095p2-75 | Diabetes and Insulin | ESPE2022

Low vitamin D levels are associated with markers of metabolic syndrome in children with newly onset type 1 diabetes mellitus

Puerto-Carranza Elsa , Muriscot-Niell Liria , Carreras-Badosa Gemma , De Zegher Francis , Lourdes Ibañez , Judit Bassols , Abel López-Bermejo

Background: Low vitamin D levels are prevalent in pediatric patients with type 1 diabetes mellitus (T1DM) and are associated with increased risk for insulin resistance, type 2 diabetes mellitus and cardiovascular disease. Little is known about associations between vitamin D levels and markers of metabolic syndrome in incident T1DM in children. The aim of our study was to analyze associations between D vitamin levels and metabolic markers in newly onset T1DM pe...

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hrp0095p2-76 | Diabetes and Insulin | ESPE2022

Fibroblast growth factor 23 in relation to calcium-phosphate metabolism and cardiovascular risk factors in patients with type 1 diabetes.

Vermeulen Stephanie , E.A. Scheffer-Rath Mirjam , T.P. Besouw Martine , van der Vaart Amarens , H. de Borst Martin , M. Boot Annemieke

Introduction: Cardiovascular disease (CVD) is the major cause of morbidity and mortality in type 1 diabetes (T1D). Recent studies implicated deregulated phosphate homeostasis in the etiology of CVD. The objective of this study is to address the relationship between the phosphate-regulating hormone fibroblast growth factor 23 (FGF23) and cardiovascular risk factors in adults with and without type 1 diabetes (T1D).Methods:...

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hrp0095p2-77 | Diabetes and Insulin | ESPE2022

Rituximab Role in Preservation of Pancreatic Beta Cells in Patients Newly Diagnosed With Type 1 Diabetes Mellitus: A Report of 2 Palestinian Cases.

Eida Hasan , Mansour Ahmad , Eleyan Tamara

Type 1 diabetes mellitus (T1DM) is a condition caused by the clonal generation of autoantibodies by B cells. Rituximab, an immunosuppressive agent, has been shown in studies to protect pancreatic function in individuals newly diagnosed with type 1 diabetes mellitus (T1DM). We investigated the effects of rituximab in two individuals with newly diagnosed T1DM. Case 1 was a 10-year-old boy, and Case 2 was a 4-year-old girl, both of whom had T1DM. Insulin secretion capability was ...

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hrp0095p2-78 | Diabetes and Insulin | ESPE2022

Complications of Covid-19 on the thyroid gland functioning

Ismailov Said , Alimova Nasiba , Jumaeva Hilola , Nasirova Khurshida

Annotation: Pandemics of coronoviral infection continues affecting the wold community, and with the comprehension of its pathological physiology an interest in endocrine effects ofSARS-CoV-2 grows too. It was determined, that the main target organs affected by SARS-CoV-2 were lungs and immune system, while it is still not clear if SARS-CoV-2 has any impact on the thyroid function. In patients infected with SARS-CoV, coronovirus relevant to SARS-CoV-2, damage o...

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hrp0095p2-79 | Diabetes and Insulin | ESPE2022

Association of type 1 diabetes mellitus with autoimmune diseases in children in the Department of Endocrinology-Diabetology and Nutrition at Mohammed VI University Hospital Center Oujda

Charif Hajar , Yagoubi Latifa , Ourdi Amal , Youssra Laalaoua , Assarar Imane , Messaoudi Najoua , Rouf Siham , Latrech Hanane

Introduction: Type 1 diabetes is frequently accompanied by other autoimmune diseases that can sometimes be integrated into autoimmune polyendocrinopathies. Through this work, we sought to describe the association of autoimmune diseases with type 1 diabetes in children.Patients and Methods: This is a retrospective and descriptive study, including 354 type 1 diabetic patients hospitalized in the Department of Endocrinology...

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hrp0095p2-80 | Diabetes and Insulin | ESPE2022

A MODY2 pedigree with GCK gene mutation and literatures review

Huang Siqi , Hou Lele , Meng Zhe , Liang Liyang

Objective: To report a family with MODY2 associated with GCK gene mutation and improve clinicians' understanding of this gene mutation.Methods: The clinical manifestations, laboratory examinations and genetic test results of a MODY2 family diagnosed and treated in our hospital were analyzed retrospectively, and the related literatures were reviewed.Results: The patient is a 6-...

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hrp0095p2-81 | Diabetes and Insulin | ESPE2022

Steroid-induced diabetes mellitus in children and adolescents: risk factors, course features, treatment specifics and prognosis on example of 10 patients

Frolova Elena , Shirokova Irina , Makretskaya Nina

Background: SIDM is not a common complication of high-dose glucocorticoid therapy (HD-GC) in pediatric practice. There are no clear generally accepted approaches to SIDM treatment. In 10 cases, we present the identified patterns of predictors, course, features of the treatment of SIDM in children and adolescents.Methods: 10 case histories of children with SIDM were analyzed. 4 boys, 6 girls, age 8-17.5 years, median 15 y...

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hrp0095p2-82 | Diabetes and Insulin | ESPE2022

An unusual combination: Wolfram Syndrome Type 1 with type-1-Diabetes mellitus

Karatsiolis Platonas , Kamrath Clemens , Rakicioglu Hande , A. Wudy Stefan

Wolfram Syndrome Type 1 also known as DIDMOAD syndrome is an autosomal recessive genetic disorder, characterized by major criteria diabetes mellitus and optic atrophy under the age of 16, as well as minor criteria diabetes insipidous, optic atrophy and diabetes mellitus over the age of 16 years deafness, neurological signs, renal tract structural or function abnormalities, loss of function mutation in WFS1 or CISD2 gene and or family with Wolfram syndrome. Other features could...

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hrp0095p2-83 | Diabetes and Insulin | ESPE2022

Arterial Hypertension and Insulin-Dependent Diabetes : Experience Of The Consultation at The Children’s Hospital In Rabat

Touzani Asmae , Mohamed.Lahrichi Mohamed , Benhamou Badia , Bennani Naima , .Bencherifa Noureddine.Bencherifa1 , Chabraoui Layachi , Lyoussi Badia , Balafrej Amina

Hypertension is a frequent chronic pathology in young diabetics. The association of diabetes and hypertension represents a high risk of morbidity and premature cardiovascular mortality. The aim of this study was to evaluate the frequency of hypertension in young diabetics and to assess the associated morbid factors.Patients and Methods: 357 diabetics aged 3 to 27 years (mean age: 10 years), were followed at the Children's Hospital o...

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hrp0095p2-84 | Diabetes and Insulin | ESPE2022

Assessment of serum concetrations of decorin, vaspin and kallistatin in children with type 1 diabetes

Polkowska Agnieszka , Bossowski Filip , Żelazowska-Rutkowska Beata , Marcinkiewicz Katarzyna , Nesterowicz Miłosz , Leoniuk Rafał , Bossowski Artur

The increasing knowledge on the functions of gastric peptides and adipokines in the body allows the assumption of their major role linking the process of food intake, nutritional status, and body growth, largely through the regulation of glucose metabolism and insulin resistance. The aim of the study was the assessment of serum levels of selected gastric peptides and adipocytokines in children with type 1 diabetes, with respect to the disease duration. The study included 88 ch...

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hrp0095p2-85 | Diabetes and Insulin | ESPE2022

Growth Monitoring in children With Type 1 Diabetes: A Single Center Experience.

Akkurt Aycan , Gul Siraz Ulku , Hatipoglu Nihal

Type 1 diabetes mellitus (TIDM) is a very familiar chronic disease among pediatric endocrinologists. It is known that chronic diseases can affect their growth velocity and final height. The aim of the study is to determine how TIDM affects children's growth velocity during the childhood period.Material-Method: This cohort study used data from patients with TIDM participating in our clinic for the last 13 years. The patient had other...

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hrp0095p2-86 | Diabetes and Insulin | ESPE2022

Type 1 diabetes in children: What are the particularities?

Ourdi Amal , Hajar Charif , Latifa Yagoubi , Najoua Messaoudi , Soumia Berrabeh , Siham Rouf , Hanane Latrech

Introduction: Children’s type 1 diabetes is a rare entity, its prevalence is still poorly known, which makes its diagnosis, therapeutic management and prognosis increasingly difficult and uncodified. The purpose of our study is to report the experience of the Endocrinology - Diabetology and Nutrition Department in the management of diabetes in children.Methods: This is a retrospective, descriptive study including 1...

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hrp0095p2-87 | Diabetes and Insulin | ESPE2022

100 years with insulin. Implementation of analogs and technology in our environment

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , José Espina-Diez Maria

Almost 100 years ago, a major turning point in the life expectancy of people with diabetes around the world was reached with the discovery of insulin. In 1936, Hagedorn had the ingenious idea of combining insulin with a protein, protamine, and zinc and his NPH was used almost mainly in pediatrics until the end of 2003, when glargine U100 made its appearance.Objective: To evaluate the clinical experience in the incorporation of different ...

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hrp0095p2-88 | Diabetes and Insulin | ESPE2022

Association of type 1 diabetes mellitus with autoimmune diseases in children in the Department of Endocrinology-Diabetology and Nutrition at Mohammed VI University Hospital Center Oujda

Charif Hajar , Yagoubi Latifa , Ourdi Amal , Laalaoua Yousra , Assarrar Imane , Messaoudi Najoua , Rouf Siham , Latrech Hanane

Introduction: Type 1 diabetes is frequently accompanied by other autoimmune diseases that can sometimes be integrated into autoimmune polyendocrinopathies. Through this work, we sought to describe the association of autoimmune diseases with type 1 diabetes in children.Patients and Methods: This is a retrospective and descriptive study, including 354 type 1 diabetic patients hospitalized in the Department of Endocrinology...

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hrp0095p2-89 | Diabetes and Insulin | ESPE2022

Design, certification and evaluation of an Insulin Infusion Therapy Care and Education Program (PAETII) in children/adolescents in a Pediatric Unit

J. Chueca Maria , Gabari Mercedes , Burillo Elisabeth , Berrade Sara , Herrero Sara , Francisco Laura , Lopez de Dicastillo Ana , Andres Carlos

A structured program of therapeutic education is essential to achieve a good result from the use of technology in the treatment of diabetes.Objectives: Facilitate knowledge, skills and aptitudes to patients and their families in therapy. Promote the capacity for self-management and adherence to treatment. Provide ongoing support to patients. Improve clinical outcomes, health status and quality of life.Metho...

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hrp0095p2-90 | Diabetes and Insulin | ESPE2022

Contribution of 25 Hydroxy Vitamin D to the Risk of Development of Type 1 Diabetes in Children

Touzani Asmae , Cadario Francesco , Chabraoui Layachi , Bennani Naima , Imane Zineb , Amhager Samah , Balafrej Amina.

Objectives: To study the status of vitamin D (25-hydroxyvitamin D, active form) in diabetic an non-diabetic children in comparison with that of Moroccan children who have immigrated to Italy.Material and Methods: 25-hydroxyvitamin D levels were measured by chemiluminescence during the spring-summer season.Patients and Methods: Our cohort consisted of 25 subjects including 17 (9 Boy...

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hrp0095p2-91 | Diabetes and Insulin | ESPE2022

Presentation of Newly Diagnosed Type1 Diabetes Mellitus

Khan Khalid

Children with early signs and symptoms of Type 1 Diabetes need to be diagnosed promptly, before they become acutely unwell with diabetic ketoacidosis (DKA). Early diagnosis and optimal management of established DKA is key to reducing morbidity and mortality. To follow the evidence based standards. To assess whether the newly diagnosed type 1 diabetes were in DKA at presentation or not. To assess compliance to guidelines on admission. As per retrospective cohort study, charts o...

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ESPE Abstracts

60th Annual ESPE (ESPE 2022)

BiosciAbstracts