ESPE Abstracts

Background: Non-endocrine pituitary tumors (NEPT) correspond to expansive processes, developing at the expense of non-endocrine pituitary lodge structures. Our objective is to evaluate their prevalence and their incidence rates in Oran, Algeria.

Patients and Methods: This is a cross-sectional descriptive multicenter study in the town of Oran study. Data were collected prospectively from Avril 2014 to Mars 2015 and retrospectively from Avril 1998 to Mars 2014.

Results: 35 pituitary tumors were collected in children (age ≤15 years), 33 were non-endocrine pituitary tumors (NEPT): 12 girls and 21 boys, mean age=11.3 years. Standardized incidence ratio (SIR) 1case/100000/year. Mean consultation time was 10.5±8.3 months. Circumstances of discovery: headaches-visual disturbances (70.0%), growth retardation (20.0%), polyuropolydipsia syndrome (6.6%) and incidentalomas (3.4%). Epileptic seizures reported in 6.7%. In all of the NEPT in children, the most frequent physical signs were those of pituitary insufficiency (60.0%), Diabetes insipidus (16.7%), hypothalamic syndrome (10.0%) and cranial pair involvement (6.7%). The Complications: hypothalamic syndrome 30.8%, epilepsy 11.5%, diabetes insipidus 23%. Neuropsychiatric complications (55.1%), ophthalmological (79.8%), blindness 23%, hydrocephalus 68.7% and visual impact: altered visual field (22.1%), low visual acuity (41.9%), blindness (9.3%), occulomotor disorders (18.6%), pallor or papillary atrophy (34. 9%)

Conclusion: NEPT are more frequent and more voluminous. Their significant loco regional morbidity requires awareness for early diagnosis.