ESPE2022 Poster Category 2 Thyroid (22 abstracts)
Factors related to permanent congenital hypothyroidism
Heung Sik Kim , So Yun Park , Donghyun Lee & Seokjin Kang
Keimyung University Dongsan Hospital, Daegu, Republic of South Korea
Purpose: The purpose of this study was to retrospectively analyze the clinical, laboratory, imaging findings (sonography and Tc99m-pertechnetate scanning) in patient with congenital hypothyroidism (CH) who completed 3 years of LT4 medication.
Method: 86 patients with congenital hypothyroidism were retrospectively reviewed. Medical history, laboratory, radiologic finding at the time of CH diagnosis were evaluated. Correlation between permanent CH and factors was analyzed by independent t test and chi-squared test.
Results and conclusion: Permanent hypothyroidism was associated with TSH levels at the time of CH diagnosis, term infants, thyroid dysgenesis. Thyroid sonography was more likely to predict prognosis than scintigraphy. Half of the patients with thyroid hypoplasia and enlarged thyroid had normal thyroid function after 3 years of treatment.
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