ESPE Abstracts

Introduction: Thyroid autoimmunity in chronic urticaria is a growing process and maybe manifested before concomitant with, or several years after the appearance of the urticaria. The association of chronic urticaria with autoimmune thyroid disease has frequently been reported in adults. Limited cases have been reported in children.

Case Report: Here we describe an eleven years old girl. Who was born to non-consanguineous parents. She has a history of recurrent urticarial lesions for 1.5 years over the face, trunk and extremities. She did not respond to antihistaminic drugs. Subsequently, she was diagnosed with hypothyroidism and she was started L-thyroxin. The patient presented with generalized wheals, redness and itching of the face, trunk and extremities. Oedema of the face and extremities. The thyroid gland was not palpable. Systemic examination was unremarkable. Laboratory assessment revealed: TSH: 3.5 μIU/ml (0.7-6.4), FT4: 1.7 ng/dL (0.8-2), FT3: 3.1 pg/ml (2.4-7). Anti-Thyroglobulin antibodies: 41.6 IU/ml (2.4 -7), Anti- thyroperoxidase antibodies: 188 IU/ml (0 -34) and high IgE.

Conclusion: Screening for thyroid function may be useful in all the patients with chronic urticarial.