ESPE Abstracts

Short children who are not GH deficient, often necessitate a different strategy, especially those with acceleration of bone age, which greatly limits height poten¬tial and the time available for growth. In this setting the use of agents to delay bone maturation has been explored to improve adult height. Estrogen principally modulates epiphyseal fusion in females and males through ERα. Aromatase inhibitors (AIs) block androgen to estrogen conversion, slowing down grow...

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