ESPE Abstracts

Background: The condition when a person’s gender identity does not match the gender assigned at birth is called gender incongruence (GI). GI numbers increased tremendously over the last decade. Diabetes mellitus – type 1 and type 2 – is a severe and lifelong disease. GI combined with diabetes may potentiate the burden for affected people.Objective: The study aimed to characterize people with GI and diab...

Background: Type 1 diabetes (T1D) is characterized by chronic hyperglycemia and microvascular complications like retinopathy, nephropathy, and neuropathy in long term. Nailfold video capillaroscopy (NVC) is a non-invasive method used to examine the microcirculation in the skin. In this study, we aimed to evaluate the microvascular structure in T1D with NVC, observe capillaroscopic alterations, and reveal the relationship of capillaroscopic abnormalities with g...

Introduction: With the development and use of automated insulin delivery (AID) technologies like Advanced Hybrid Closed Loop (AHCL or Minimed 780G) system, it becomes possible to achieve tighter glycemic control. A new parameter called “Time in Tight Range” (TITR, 70-140 mg/dL) has been proposed to evaluate glycemic control in the latest consensus on the use of continuous glucose monitoring (CGM) data in diabetes research. This study aims to assess...

Key words: Type 1 diabetes mellitus; Intestinal flora; metagenomic sequencing; cytokines; AutoimmunityObjective: This study aims to verify the effect of intestinal microbiota diversity on the disease development of T1DM mice model, and to explore the mechanism of intestinal microbiota in the development of type 1 diabetes mediated by related cytokines.Method: T1DM mouse model was e...

Background: Poor glycemic control in type 1 diabetes (T1D) is linked to cardiovascular complications. Sleep duration and quality have been shown to be related to glycemic control, glucose variability, and endothelial dysfunction in adults with T1D. This study aimed to evaluate the relationship between sleep characteristics, glycemic control, glucose patterns, and endothelial function in adolescents and young adults with T1D.Metho...

Aims: Recently, our team introduced the concept of post-hypoglycemic hyperglycemia (PHH) in the context that recovery of hypoglycemia impacts cardiovascular risk. GLUREDIA study aimed to evaluate whether PHH parameters correlated with glycemic homeostasis during the first year after type 1 diabetes onset and helped to distinguish pediatric patients undergoing partial remission or not.Methods: In the GLUREDIA study, longi...