ESPE Abstracts

NASH is an increasingly relevant finding in the pediatric population affected by obesity. In adults, its evolution from this steatosis to fibrosis and its correlation with metabolic syndrome is increasingly significant. The existence of a rapid and validated screening tool in consultation would be very useful.

Main objective: To evaluate if the measurement of intraperitoneal fat measured through nutritional ultrasound, allows the diagnosis of non-fatty hepatic steatosis or metabolic risk in overweight/obese patients. To establish whether there is any type of correlation between the measurements of abdominal fat obtained by nutritional ultrasound and those obtained in routine clinical practice of these patients by means of liver ULTRASOUND if this is performed within routine clinical practice.

Material and Methods: Patients who attend the CCEE of Endocrinology for being overweight. BMI >2 SDS. MINDRAY Z50 ULTRASOUND. (Hamagawa technique) by means of abdominal adipose ULTRASOUND study (superficial subepidermal fat - stored energy, deep and intraperitoneal-risk in adults of NASH)

Results: First national validation study in pediatrics of deep ECOGRAPHY compatible with NASH vs nutritional ECO Study in 103 patients of deep ECO by radiologist and nutritional ECO. NASH 60/103 (58%). Mild distribution 50/103 (48%), moderate 9/103 (8.9%) and severe 1/103 (1%) A Mann-Whitney U test was performed. The results showed that the mean intraperitoneal fat (adipose) was statistically significantly higher among the NASH affected groups (z = -7.603, p < 0.01) at a significance level of 0.05. The cut-off point that presents a positive correlation between NASH YES/NO would be a mean of 0.93 cm CI [0.70-0.94] 95% using the Mann-Whitney U test. Sensitivity 97%. Specificity 95%.

Conclusions: There is a high prevalence of NASH in childhood obesity. The classical ECO is related by means of a linear and positive correlation with the pre-peritoneal fat mass studied by nutritional ECO.