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ESPE Abstracts (2023) 97 P1-129

ESPE2023 Poster Category 1 Growth and Syndromes (75 abstracts)

Qatar population-specific centile charts of placental weight to birth weight (PW/BW) ratio in 80 722 newborns born between the 37 th and 42 nd Weeks of Gestation: Relation to Gestational Age, and Gender.

Fawzia Alyafei , Ashraf Soliman , Nada Alaaraj , Noor Hamed & Shayma Ahmed

0
Err

HMC, Doha, Qatar

Background: Data about placental weight (PW) in relation to birth weight (BW) and gestational age (GA) are lacking in Arab countries.

Objectives: To report the specific centile charts of PW/BW ratio in a large cohort of mother/baby pairs (n= 80277) born between 37th and 42nd weeks of gestation in relation to neonatal growth characteristics and gender.

Methods: Retrospective cohort study of 80722 mothers, placentas, and newborns delivered in Hamad Medical Corporation Hospitals for 4 years (1-2016: 12- 2019) in Qatar. The information was collected from medical records. The inclusion criterion for this analysis was term singleton live births, 37+0 to 42+6 weeks gestation. According to birth size babies were divided into SGA (<10th percentile), AGA (between 10th and 90th percentiles) and LGA (> 90th percentile) Using intergrowth-21st standards

Results: The PW/BW centiles are constructed (table 1) in full term boys and girls. The PW/BW ratio is significantly bigger in SGA infants versus AGA and LGA. In addition, the PW/BW ratio was slightly but significantly in girls versus boys.

Table 1: Placenta to Birth weight ratio centiles by gestational age (weeks) for boys and girls (SGA, LGA and AGA)
All babies
Intergrowth-21st mean SD p5 p10 p25 p50 p75 p90 p95
AGA 0.203 0.026 0.158 0.169 0.187 0.203 0.219 0.235 0.245
SGA 0.219 0.039 0.154 0.165 0.192 0.224 0.245 0.264 0.276
LGA 0.195 0.025 0.157 0.165 0.179 0.193 0.208 0.226 0.238
Total 0.203 0.028 0.158 0.168 0.185 0.202 0.219 0.236 0.248
Males
Intergrowth-21st mean SD p5 p10 p25 p50 p75 p90 p95
AGA 0.200 0.026 0.157 0.167 0.185 0.201 0.217 0.232 0.241
SGA 0.216 0.039 0.152 0.162 0.187 0.220 0.242 0.260 0.274
LGA 0.193 0.024 0.154 0.163 0.177 0.192 0.206 0.222 0.235
Total 0.200 0.027 0.156 0.166 0.183 0.200 0.217 0.233 0.244
Females
Intergrowth-21st mean SD p5 p10 p25 p50 p75 p90 p95
AGA 0.205 0.027 0.160 0.171 0.189 0.206 0.222 0.237 0.248
SGA 0.223 0.039 0.156 0.170 0.197 0.227 0.248 0.267 0.278
LGA 0.197 0.025 0.160 0.168 0.181 0.195 0.210 0.229 0.241
Total 0.205 0.028 0.160 0.170 0.188 0.205 0.222 0.239 0.251

Conclusion: Increased PW/BW ratio in SGA infants may be represent a compensatory mechanism to increase the efficiency of transport functions to the growth compromised fetus. PW/BW centiles for FT infants are reported.

Volume 97

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61st Annual ESPE (ESPE 2023)

The Hague, Netherlands
21 Sep 2023 - 23 Sep 2023

European Society for Paediatric Endocrinology 

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