ESPE Abstracts

Keywords: pediatric obesity, metabolic syndrome, dyslipidemia, abdominal obesity, cardiovascular risk.

Introduction: The prevalence of pediatric obesity is rising globally as well as in Romania and so are the complications of obesity. Dyslipidemia is one of the most frequent complications and is associated with cardiovascular risk even in children or teenagers. Evaluating the degree of obesity and the correlations between dyslipidemia and metabolic syndrome is important for the primary prevention of cardiovascular diseases.

Material and method: We conducted a retrospective observational case series and case-control study between 2019-2021, with observation sheets from the Kilostop Junior Nutrition Clinic. We included 241 children and teenagers from the southern regions of Romania, with ages 3-17 (median: 11.42), 114 males (47.3%), BMI median=27.67 and median of the degree of obesity=99 %.

Results and conclusions: We performed a Fisher’s correlation and found that an obesity degree over 110% positively correlates with an abdominal circumference over the 95th centile (P=001). A negative Pierson correlation between the pathological ratio HDL cholesterol to triglycerides of 0.5 (P=0.008) and an obesity degree of over 110%. A low HDL value negatively associates with a high obesity degree (r= -0.319, P=0.00). Patients with dyslipidemia wave a higher risk of hyperuricemia (Or= 3,7, 95%CI=1,44-9,45, P=0.0062)

Conclusions: The obesity degree and visceral obesity negatively influence HDL and HDL to triglycerides ratio and children with dyslipidemia have a higher risk of hyperuricemia. A standardized cardiovascular risk evaluation method is needed even for young children to prevent the onset of cardiovascular diseases at young ages.