Previous issue | Volume 97 | ESPE2023

61st Annual ESPE (ESPE 2023)

The Hague, Netherlands
21 Sep 2023 - 23 Sep 2023

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The 61st ESPE Annual Meeting will now be taking place in The Hague, The Netherlands

Poster Category 2

Fat, Metabolism and Obesity

hrp0097p2-31 | Fat, Metabolism and Obesity | ESPE2023

Can Gender differently affect Growth and Metabolic Syndrome (MetS) Criteria in children with Classic Congenital Adrenal Hyperplasia (CAH)?

El Sayed Shayma , Soliman Ashraf , Hamed Noor , Alyafei Fawzia , Alaaraj Nada , Ahmed Shayma

we compared gender effect on growth and metabolic control with CAH. Morbidities associated with CAH, including risks of obesity, hypertension, dysglycemia, and dyslipidemia were investigated.Methods: Data from 30 children with CAH were analyzed retrospectively. They received hydrocortisone (n= 11) or prednisolone (n= 19) and fludrocortisone (0.1: 0.15 mg OD) since early infancy. The mean hydrocortisone dose = 22.5 +/- 7...

hrp0097p2-32 | Fat, Metabolism and Obesity | ESPE2023

The prevalence and risk factors of non-alcoholic fatty liver disease in obese and normal weight children in Latvia

Gailite Jurgita , Petrosina Eva , Gardovska Dace , Dzivite-Krisane Iveta

Background: Public health research shows that the prevalence of obesity is increasing rapidly not only among adults, but especially among adolescents and children. Obese children and adolescents are at risk of early chronic complications such as cardiovascular diseases, non-alcoholic fatty liver disease (NAFLD), type 2 diabetes mellitus, various types of tumors, orthopedic problems, serious psychological and neurological problems.<strong...

hrp0097p2-33 | Fat, Metabolism and Obesity | ESPE2023

Obesity-related Hypothyroidism in Children

Otilia Bizerea-Moga Teofana , Olah Orsolya , Ilieș Cristina , Flavia Brad Giorgiana , Mărginean Otilia

Key Words: obesity, subclinical hypothyroidism, childrenIntroduction: There is a growing interest in the relationship between obesity and thyroid dysfunction, even more so nowadays when obesity has become a widespread global issue. Initially believed to be the cause of obesity, the risk of developing hypothyroidism may be increased in obese children due to adaptive mechanisms. The study aims to evaluate the prevalence of...

hrp0097p2-34 | Fat, Metabolism and Obesity | ESPE2023

Case Report: Massive Obesity secondary to a Homozygous MC4R mutation in a 3-year-old Boy

Gillis David , Hefter Ari , Edri Edri Shalom , Strich David

We present a 3-year-old boy with massive obesity and hyperphagia. His appetite symptoms were evident from age 3 months, and his parents report he has an insatiable appetite, and seeks food constantly. At presentation to our clinic, his BMI was 37.21 Kg/m² [+ 6.87 SDS]. Sleep apnoea is suspected, for which he is undergoing evaluation. Parents are second cousins. Both parents are moderately obese, but his siblings are normal weight for age. The mother did not have a history...

hrp0097p2-67 | Fat, Metabolism and Obesity | ESPE2023

The outcome of management for childhood obesity during COVID19 pandemic (2019-2021) in Qatar

Hamed Noor , Shaat Mona , Soliman Ashraf , Alyafei Fawzia , Alaaraj Nada , Ahmed Shayma

Introduction: Obesity is serious health concern that affect the children during pandemic due to school closing and shifting to online teaching with suspension of almost all physical activity. In addition, many overweight and obese children had irregular meal timing, frequent snacking, and increased screen time at home.Objectives: To study the effect of COVID 19 on weight gain during the lock- down and shifting to online ...

hrp0097p2-68 | Fat, Metabolism and Obesity | ESPE2023

Gut Hormones in Malnourished infants and children: Important Role in Adaptation.

Soliman Ashraf , Alaaraj Nada , Alyafei Fawzia , Hamed Noor

The gastrointestinal (GI) tract is the body's largest endocrine organ producing hormones that have important sensing and signaling roles in the regulation of energy homeostasis and immune mechanisms.Objectives and Methods: We performed electronic literature systematic review using PubMed, Google Scholar, and Web of Sciences with the aim of providing an update on the changes occurring in gut hormones (Ghrelin, GLP-1 and PYY, insulin,...

hrp0097p2-69 | Fat, Metabolism and Obesity | ESPE2023

A Young Woman with Morbid Early Onset Obesity, Progressive Hypothalamic-Pituitary Dysfunction, Bilateral Optic Nerve Atrophy, and a Combination of Variations in Four Genes Involved in Hypothalamic Satiety Signaling Pathways

Bullock Julianne , Bhangoo Amrit , Dreimane Daina

Background: Leptin receptor (LepR) deficiency is an autosomal-recessive rare condition causing early-onset severe obesity, hyperphagia, hypogonadotropic hypogonadism (HH), hypothyroidism, and/or growth hormone deficiency (GHD). Cohen syndrome is a variable autosomal recessive genetic disease caused by mutations in the VPS13B gene causing central obesity, characteristic facial features, hypotonia, non-progressive intellectual deficit, neutropenia,...

hrp0097p2-70 | Fat, Metabolism and Obesity | ESPE2023

Association of osteoprotegerin and metabolic status in obese children.

Mikhno Hanna , Solntsava Anzhalika

Objective: determination of changes in metabolic status and osteoprotegerin (OPG) concentrations in obese children.Methods: We examined 220 children in the University Hospital (Minsk) from 2022 to 2023 yrs. Their anthropometric parameters (height, weight, body mass index (BMI)) were determined. Blood levels of OPG, insulin were determined. All children were divided into 2 groups: group 1 children with morbid obesity (MO)...

hrp0097p2-71 | Fat, Metabolism and Obesity | ESPE2023

The first case report of a child with progeria syndrome in Oman

Almamari Moza , Ahmed Malaz , ALSaffar Hussain , ALsaidi Suliman

Hutchison-Gilford progeria syndrome (HGPS) is a rare genetic disorder which is characterized by aging fast in affected individuals. The prevalence of HGPS is around of 1 in 20 million approximately. The exact etiology is not very well known, However it is believed to be an autosomal dominant disorder that occurs due to point mutations in lamin A (LMNA) gene. In this case report we share the challenges of being the first presented case in Oman. A 6 years old Omani boy diagnosed...

hrp0097p2-112 | Fat, Metabolism and Obesity | ESPE2023

Evaluation of Triglycerides to High Density Lipoprotein Cholesterol Ratio (TG/HDL-C) as a Predictor of Insulin Resistance among Obese Children and Adolescents, single center experience.

Fawaz Lubna , Abdelmoneim Mohamed , Abdel salam Reda , Shamma Radwa

Key words: Insulin resistance, triglycerides to high-density lipoprotein cholesterol-(HDL-C), HOMA-IR.Background: Childhood Obesity is a chronic metabolic disease. The fundamental disorder related to obesity is Insulin Resistance (IR). The gold standard method to measure IR is by use the hyper insulinemic euglycemic clamp, rarely performed in children because of its invasiveness, complexity, time consumption and high cos...

hrp0097p2-132 | Fat, Metabolism and Obesity | ESPE2023

Body composition changes during interventions to treat obesity in children

Soliman Ashraf , Hamed Noor , Shaat Mona , Alaaraj Nada , Alyafei Fawzia , Alyousef Doaa

Introduction: Nutrition, bodily activity, and behavior-modifying practices are recognized interventions in managing obesity. Our aim was to review available information on the short-term effects of intervention (3-4 months) on body composition of overweight and obese children and adolescents.Methods: We reviewed the anthropometric data (Weight, height (HtSD), and BMI of 16 obese children aged 12 +/- 2.2 years. Body compo...

hrp0097p2-133 | Fat, Metabolism and Obesity | ESPE2023

Integrated care for childhood obesity within the medical and municipal domain

van Mil Edgar , Koetsier Leandra , Seidell Jaap , Sijben Marian , Stroo Judith , van der Velde Marian , Halberstadt Jutka

Childhood obesity is a chronic disease with detrimental effects on health and wellbeing. Treatment was traditionally focused on reducing caloric intake and increasing energy expenditure. However, considering the global increase in prevalence in obesity, especially in the paediatric age range, this approach is insufficient and transition to new initiatives is needed. Obesity is a complex disease resulting from the interaction of multiple underlying factors, including personal c...

hrp0097p2-134 | Fat, Metabolism and Obesity | ESPE2023

Short-term data of the newly opened pediatric obesity center in Ankara

Kocaay Pınar , Adıgüzel Kezban , Tepe Derya , Boyraz Mehmet

Childhood obesity has emerged as an important public health problem in the worldwide. It is important to follow these cases in multidisciplinary centers at an early age in order to prevent metabolic and psychosocial comorbidities that may develop. Bariatric surgery is a treatment method whose frequency is increasing in adolescent obesity. In the study, the 6-month results of the patients who applied to the obesity center were shared.Materials-Met...

hrp0097p2-135 | Fat, Metabolism and Obesity | ESPE2023

The influence of Vitamin D on the physical fitness of obese children

Šandrk Beslać Marija , Bilinovac Željka , Nikolić Jelena , Džida Sanja , Koršić Mirko

Introduction: Obesity and vitamin D deficiency are global public health problems. There is evidence of a reciprocal link between vitamin D deficiency and obesity. Both conditions are risk factors for the development of chronic diseases, primarily insulin resistance and diabetes mellitus type 2, and contribute to a decrease in physical fitness (PF). The aim of this study was to determine the effectiveness of vitamin D supplementation on PF of obese children dur...

hrp0097p2-177 | Fat, Metabolism and Obesity | ESPE2023

Correlations between the degrees of obesity and dyslipidemia in a pediatric population from Romania

Amalia Ioana Arhire , Papuc Teodora , Miruna Sanziana Chiper , Chiriac Malina , Stoica Alexandra , Tambrea Elena

Keywords: pediatric obesity, metabolic syndrome, dyslipidemia, abdominal obesity, cardiovascular risk.Introduction: The prevalence of pediatric obesity is rising globally as well as in Romania and so are the complications of obesity. Dyslipidemia is one of the most frequent complications and is associated with cardiovascular risk even in children or teenagers. Evaluating the degree of obesity and the correlations between...

hrp0097p2-207 | Fat, Metabolism and Obesity | ESPE2023

The association between physical activity and 25-OH vitamin D levels

Zeynep Altun Ekin , Bilir Pelin , Torel Ergur Ayca

In children and adolescents, vitamin D deficiency negatively affects muscle physiology, exposing them to increased muscle damage and pain, stress fractures, and tendon structures. In addition, free radicals released when the body is exposed to oxidative stress after exercise can cause DNA damage. Vitamin D plays an important role in removing these radicals. The purpose of this study is to investigate the relationship between physical activity and 25- OH vitamin D in obese chil...

hrp0097p2-208 | Fat, Metabolism and Obesity | ESPE2023

THe relationship between sunlight exposure and insulin resistance

Zeynep Altun Ekin , Bilir Pelin , Torel Ergur Ayca

Childhood obesity (CO) is an important risk factor for the development of many chronic metabolic diseases in adulthood. Understanding the mechanisms that promote childhood obesity and eliminating these causes in childhood are critical for later life. One of the major complications of obesity is insulin resistance. The purpose of this study is to investigate the relationship between sunlight exposure and insulin resistance in childhood. Specifically, it examines how the duratio...