Previous issue | Volume 97 | ESPE2023

61st Annual ESPE (ESPE 2023)

The Hague, Netherlands
21 Sep 2023 - 23 Sep 2023

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The 61st ESPE Annual Meeting will now be taking place in The Hague, The Netherlands

Rapid Free Communications

Diabetes and insulin 1

hrp0097rfc5.1 | Diabetes and insulin 1 | ESPE2023

Tear proteomics profile in children and adolescents with type 1 diabetes mellitus

Angelopoulou Eleni , Anargyros Vasilakis Ioannis- , Kitani Rosa-Anna , Letsou Konstantina , Lygirou Vasiliki , Zoidakis Jerome , Samiotaki Martina , Kanaka- Gantenbein* Christina , Nicolaides* Nicolas

Background and Purpose: Previous studies have shown differences in serum, plasma, or saliva proteomics profile in patients with type 1 diabetes mellitus (T1DM), compared with healthy controls. The purpose of this prospective study is to identify the tear proteomics profile in children with T1DM that are followed at the Diabetes Center of the First Department of Pediatrics of the National and Kapodistrian University of Athens, at “Aghia Sophia” Chil...

hrp0097rfc5.2 | Diabetes and insulin 1 | ESPE2023

Comparison of Optical Coherence Tomography Angiography Findings in Children with Type 1 Diabetes Mellitus and Autoimmune Thyroiditis with Healthy Children

Anıl Korkmaz Hüseyin , Devebacak Ali , Mert Erbaş ibrahim , Değirmenci Cumali , Uyar Nilüfer , Afrashi Filiz , Özkan Behzat

Aim: The study aimed to assess the development of early diabetic retinopathy (DR), one of the microvascular complications, in patients with isolated type 1 diabetes mellitus (DM) (group 1), type 1 DM with a diagnosis of autoimmune thyroiditis (AT) (group 2), and healthy controls (group 3), which were matched for age, sex, number, and body mass index for comparison.Methods: In this prospective and observational study, gro...

hrp0097rfc5.3 | Diabetes and insulin 1 | ESPE2023

3 Screen ICA ELISA–A new tool to identify pre-clinical diabetes in first-degree relatives of patients with type 1 diabetes (pre-d1abetes study)

Bossowski Artur , Noiszewska Klaudyna , Polkowska Agnieszka , Zasim Aneta , Jamiolkowska Milena , Mysliwiec Malgorzata , Szadkowska Agnieszka , Mazur Artur , Jarosz-Chobot Przemyslawa , Szypowska Agnieszka , Chobot Agata , Nazim Joanna , Zubkiewicz Agnieszka , Ben-Skowronek Iwona , Niechcial Elzbieta , Walczak Mieczyslaw , Jozwa Anita , Mincewicz-Wysocka Marta , Robak-Kotna Katarzyna , Chen Shu , Furmaniak Jadwiga , Smith Bernard

Introduction: Overt clinical symptoms of type 1 diabetes (T1D) are often preceded by a pre-clinical stage of varying duration. Diagnosis of the pre-clinical stage is difficult and is based on the presence of specific islet autoantibodies in the subject's blood. Objectives: Apparently healthy first-degree relatives of patients with T1D were tested using the 3 Screen ICAELISA (RSR Ltd) for combined testing for autoantibodies to GAD65 (glutamic acid decarbox...

hrp0097rfc5.4 | Diabetes and insulin 1 | ESPE2023

Effect of probiotic on glycemic control in children with type 1 diabetes: A randomized controlled trial

Elshebrawy Hadeer , El-Hawary Amany , El-Husseiny Ahmed , Laymoun Wafaa

Background: Studies in animal models and humans with type 1 diabetes mellitus (T1DM) have shown that probiotic supplementation leads to decreased proinflammatory cytokines (responsible for damaging β-cells of the pancreas), improved gut barrier function, and induction of immune tolerance.Objective: To study the effect of supplementation of probiotics in children with T1DM on glycemic control, insulin total daily dos...

hrp0097rfc5.5 | Diabetes and insulin 1 | ESPE2023

Syndrome of hypoglycemia unawareness in children with type 1 diabetes: clinical contribution of Clark and Gold questionnaire

Obermannová Barbora , Kyzlíková Kamila , Plachý Lukáš , Neuman Vít , Průhová Štěpánka , Petruželková Lenka , Koloušková Stanislava , Šumník Zdeněk

Introduction: For diagnosis of syndrome of hypoglycemia unawareness is used Clarke and/or Gold questionnaire. Frequency of this syndrome in children with type 1 diabetes (T1D) and its association with parameters of metabolic control including the CGM data are not well characterised.Aims and methods: The aim of our study was to find the prevalence of this syndrome in children with T1D (age 8-19 years) followed at our depa...

hrp0097rfc5.6 | Diabetes and insulin 1 | ESPE2023

Do females with Type 1 Diabetes have puberty earlier?

Cordero Pearson Andrea , Lucía Gomez Gila Ana , Navarro Moreno Constanza

Background: In the past, the majority of the pacients with Type 1 Diabetes (DM1) had late puberty due to hipogonadotropic hipogonadism as a result of insulin deficiency. However, the use of intensive insulin therapy nowadays, results in higher BMI what can lead to an earlier puberty. Insulin administered subcutaneously is not processed by the liver, which implies increased exposure to this hormone in the ovary leading to greater activation of theca and granulo...