Previous issue | Volume 97 | ESPE2023

61st Annual ESPE (ESPE 2023)

The Hague, Netherlands
21 Sep 2023 - 23 Sep 2023

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The 61st ESPE Annual Meeting will now be taking place in The Hague, The Netherlands


Novel insights and innovations in diabetes

hrp0097s4.3 | Novel insights and innovations in diabetes | ESPE2023

Physical interaction between beta and delta cells

Rorsman Patrik

Diabetes mellitus is a bihormonal disorder involving both insufficient insulin secretion (from the beta-cells(and dysregulation of glucagon secretion (from the alpha-cells). In healthy people, a fall in plasma glucose increases glucagon and stimulates counterregulatory hepatic glucose production. This response is impaired in many patients with type-1 diabetes (T1D). Why this defect develops is unknown but it may lead to fatal hypoglycaemia, which accounts for up to 10% of the ...