ESPE Abstracts

Introduction: Prader-Willi Syndrome (PWS) is the most frequent cause of genetic obesity. It has been described that these patients require a reduction in caloric intake of 20- 40% compared to general population. Since 2000, with the approval of growth hormone (GH), the evolution of obesity has changed and it seems that caloric requirements could be different.

Methodology: Observational, descriptive, cross-sectional and retrospective study about caloric intake in children 6 months-12 years old diagnosed with PWS and under growth hormone treatment. Dietary records were used to estimate energy intake and the difference between their caloric intake and the theoretical accepted for healthy children was calculated.

Results: 25 participants were included. 52% (n=13) were boys and 48% (n=12) girls. The mean age was 6.72 years (±2.81 SDS). The median age of initiation of GH was 1.4 years (IQR: 0.78, 2.29). 68% (n=17) were of normal weight and 32% (n=8) were overweight or obese. The mean daily energy intake was 1,208 kcal/d (±186 SDS), 96.83% (±18.66 SDS) compared to that recommended by the Henry predictive equation.

Conclusions: Patients with Prader-Willi Syndrome treated with growth hormone consume an average of 96.83% calories of those needed by a healthy child. We should rethink the classic reduction of 20-40% in these children