ESPE Abstracts (2023) 97 P2-105

1Pediatric Endocrinology unit, Pediatric department, Puerta del Mar University Hospital, Cadiz, Spain. 2Endocrinology department, Puerta del Mar University Hospital, Cadiz, Spain. 3Biomedical Research and Innovation Institute of Cadiz (INIBiCA), Cadiz, Spain. 4Mother and Child Health, and Radiology Department, Faculty of Medicine, Cádiz University, Cadiz, Spain. 5otorhinolaryngology department, Puerta del Mar University Hospital, Cadiz, Spain


Introduction: A transgender individual’s voice may contribute to the negative psychosocial outcomes. Some studies have shown that an incongruence between one’s voice and internal gender identity can be a potential source of ongoing psychological distress and could impact on their social interactions, employment outcomes, and invite verbal or physical harassment. This study was aimed to examine whether early puberal blockage (PB) impacts on self perception of voice in trangender girls in adolescence.

Methods: A cross-sectional study was performed including trans girls younger than 18 years old followed in our transgender reference unit that has started puberal blockage. Transsexual Voice Questionnaire (TVQ), Voice Handicap Index (VHI-30) and acoustic analysis with /a/ for F0 obtained from all participants after sign informed consent by them and the main caregiver. We classified in 2 groups: Early PB (pubertal stage <3) and late PB (Pubertal stage > 3). Non-parametric test were

Results: 28 trans adolescents were included, 7 with Early pubertal blockage and 21 with late pubertal blockage. Age at BP initiation was found but No difference in blockage duration between groups was found at voice questionnaire and acoustic analysis time. Higher score on VHI-30 and TVQ (worst voice perception) and lower F0 was observed on late BP with difference statistically significant.

Early PB Late PB P-value
N 7 21 -
Current Age (years) 14.3 (13.3-14.5) 17.6 (16.6-18.5) <0.001
BP age initiation (years) 11 (10.8 - 12.7) 15.4 (14.2 -16.3) 0.475
BP duration (years) 3.3 (2.2-4.1) 2.7 (1.9-3) 0.475
VHI-30 score 4 (0-26) 31 (11-56) 0.023
TVQ score 31 (30-39) 70 (55-87) <0.001
F0 227 (216-257) 135 (120-140) 0.001

Conclusion: Trans adolescents with early pubertal blockage show lower score in VHI-30 and TVQ questionnaire and Higher F0 in acoustic analysis, which support a good voice perception. This study supports that testosterone has acted irreversibly virilizing to the voice if they already went through male puberty.

Volume 97

61st Annual ESPE (ESPE 2023)

The Hague, Netherlands
21 Sep 2023 - 23 Sep 2023

European Society for Paediatric Endocrinology 

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