hrp0098p2-209 | Multisystem Endocrine Disorders | ESPE2024

Acute renal failure as first presentation of APECED in infancy

Yankova Stefka , Balabanski Lubomir , Yaneva Slavyana , Atanasoska Maya , Yaneva Natasha , Arshinkova Margarita , Stoeva Iva

Introduction: Adrenal insufficiency is a rare, but potentially fatal medical condition, most frequently congenital in children. Rapid and accurate diagnosis is imperative for effective treatment. A growing number of causative gene mutations in overlapping clinical phenotypes and different syndromes which share adrenal insufficiency as one of the main characteristics were published recently.Case Presentation: An infant (b...

hrp0095p1-323 | Growth and Syndromes | ESPE2022

Assessment of linear growth and weight gain after early infantile surgical repair of tetralogy of Fallot (TOF)

Soliman Ashraf , Ali Hamdy , Yassen Haytham , Mahmoud Nazla , Itani Maya

The benefits of surgical repair on long term growth in children with tetralogy of Fallot (TOF) have been variable. Surgery undertaken beyond infancy has often been associated with a residual degree of growth impairment. Primary repair of during early infancy was adopted in many centres, if clinically indicated. We examined the effects of full early surgical correction of TOF on linear growth for 2 years postoperatively. Anthropometric data of infants with TOF before and after ...

hrp0095p1-329 | Growth and Syndromes | ESPE2022

Associations between Eating Patterns of Adolescents and Their Height and Weight, A Comparison Between Genders

Zur Maya , Fisch-Shvalb Naama , Phillip Moshe , Yackobovitch-Gavan Michal

Rationale: Adequate nutrition is essential for normal growth in childhood and adolescence. The high growth rate during adolescence demands high amounts of energy and various nutrients. During puberty, unlike infancy and early childhood, boys and girls of the same age have gender-specific nutritional needs. Our aim was to examine the associations between the dietary intake of male and female adolescents and their anthropometric measures.<...

hrp0095p1-518 | Growth and Syndromes | ESPE2022

Variable post-operative growth pattern in infants with transposition of great arteries (TGA) after neonatal arterial switch operation

Soliman Ashraf , Ali Hamdy , Mahmoud Nazla , Itani Maya , Yassen Haytham

The arterial switch operation (ASO) represents a remarkable success in the treatment of cyanotic congenital heart disease, with survival rates approaching 100%. The effect of infantile deep hypothermic circulatory arrest and hypoxia on post-operative linear growth is not studied. Growth data were recorded and analyzed in 12 infants with d-TGA who underwent switch operation (anatomical correction) in the early neonatal period for 18 months.Results...

hrp0092p2-296 | Thyroid | ESPE2019

Progressive thyroid dysfunction in infants with Down Syndrome; Trisomy 21 (DS): Effect on Linear Growth

Alaaraj Nada , Soliman Ashraf , Mohammed Shayma , Itani Maya , Khalil Ahmed

Hypothyroidism is the most frequent thyroid abnormality in DS. It can be either congenital, with or acquired at any age after birth. It can be clinical or subclinical disorder. More evidence is required regarding the progressive development of thyroid dysfunction with age.Aim and Methods: We measured thyroid function (Free T4 and TSH) and Anti TPO level in 37 infants with DS at birth, during their first year and after ~ 2.5 years of...

hrp0092p3-153 | Growth and Syndromes (to include Turner Syndrome) | ESPE2019

Prevalence of Thyroid Dysfunction and Associated Autoimmune Disorders in Young Children with Down Syndrome (DS); A Cohort Study.

Alaaraj Nada , Soliman Ashraf , Itani Maya , Mohammed Shayma , Khalil Ahmed

There is an intriguing association between DS and thyroid abnormalities, which include sub-clinical, overt hypothyroidism, hyperthyroidism, and positive thyroid Antibodies. The prevalence of these abnormalities varies considerably depending on the diagnostic criteria and the selected population which includes sample size and age group.Aim: To measure the prevalence of thyroid dysfunction and associated autoimmunity in children with Down ...

hrp0092p3-161 | Growth and Syndromes (to include Turner Syndrome) | ESPE2019

The Effect of Thyroxine Treatment on Linear Growth and Weight Gain in Infants and Children with Down Syndrome (DS) and High TSH Versus Children with DS and Normal Thyroid Function: A Controlled Study

Alaaraj Nada , Soliman Ashraf , Itani Maya , Mohammed Shayma , Khalil Ahmed

Background: Subclinical hypothyroidism is the most common in DS. Thyroxin administration to improve growth early in life is still controversial.We measured linear growth (BMI, height SDS (HtSDS) and weight gain/day ) in 3 groups of infants and young children with Down syndrome (trisomy 21) and divided them retrospectively into 3 groups according to their thyroid function. Group 1 (n = 25) with normal FT4 and TSH, group 2 (n = 20)...

hrp0082p1-d3-14 | Adrenals &amp; HP Axis (1) | ESPE2014

Clinical, Biological and Genetic Characteristics of 48 Pediatric Patients with Micronodular Adrenal Hyperplasia (MAH)

Rothenbuhler Anya , Gourgari Evgenia , Lodish Maya , Stratakis Constantine

Background: Micronodular adrenal hyperplasia (MAH) is a rare disease.Objective: Describe the clinical, biological and genetic characteristics of micronodular adrenal hyperplasia (MAH) in children.Method: Retrospective study based on medical records (from the NIH and Bicêtre Hospital) of 47 pediatric patients (age <18 years at first signs of disease) with ACTH-independent Cushing syndrome (AICS) due to MAH proven histologic...

hrp0094p2-296 | Growth and syndromes (to include Turner syndrome) | ESPE2021

Comparing the efficacy of nutritional supplementation of different caloric concentrations on linear growth and weight gain in late childhood, a longitudinal study.

Soliman Ashraf , Itani Maya , Jour Celine , Alyafei Fawzia , Adel Ashraf ,

We evaluated the growth parameters of 30 children with low weight gain who did not have any systemic illnesses and assessed their response to nutritional supplementation using two different formula supplements (1cal/1 ml) versus 1.5 cal/1ml) for one year.Patients and Methods: Thirty underweight children (BMI SDS < -1.5), aged 9 ±4 years, were divided into two groups according to the type of NS given by different dietitians. Group 1 included 10 c...

hrp0095fc4.3 | Fat, Metabolism and Obesity | ESPE2022

Impaired Brain Satiety Responses by Functional Neuroimaging After Weight Loss Therapy in Children with Obesity

Roth Christian , Melhorn Susan , DeLeon Mary , Rowland Maya , Elfers Clinton , Huang Alyssa , Saelens Brian , Schur Ellen

Background: Obesity interventions often result in increased motivation to eat after weight loss.Objective: We investigated relationships between obesity outcomes and changes in brain activation by visual food cues and hormone levels in response to obesity intervention by family-based behavioral treatment (FBT).Design, Methods, and Participants: Functional neuroimaging and plasma ho...