hrp0098p3-241 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2024

The curious case of a boy with cryptorchidism

Lezzi Marilea , Comes Fabio , Villirillo Antonietta , Gallo Francesco

Objective: This study aims to investigate the cause of cryptorchidism in a young boy.Case report: A 12 years old boy was admitted at our department for fever and lack of appetite. During physical examination, right cryptorchidism and subcoronal hypospadias were evident. Left testicle was in scrotum and it was of 4 ml in volume. In his past clinical history, he had many urological evaluations for the right testicle and sp...

hrp0092p1-346 | Fat, Metabolism and Obesity (2) | ESPE2019

Non-Invasive Assessment of Liver Steatosis: Usefulness of Elastography in Obese Children – a Pilot Study.

Corica Domenico , Aversa Tommaso , Bottari Antonio , Pepe Giorgia , Morabito Letteria , Curatola Selenia , Spinuzza Antonietta , Alibrandi Angela , Ascenti Giorgio , Wasniewska Malgorzata

Introduction: Non-alcoholic fatty liver disease (NAFLD) is diagnosed in up to 60% of overweight children. Diagnosis and management of NAFLD is challenging due to the lack of non-invasive imaging biomarkers. Ultrasound (US) is the most widely non-invasive method used to identify liver steatosis, however it has low sensitivity to detect mild steatosis and to quantify hepatic fibrosis. Liver Elastography (LE) is a non-invasive methodology used to evaluate hep...

hrp0097p1-538 | Multisystem Endocrine Disorders | ESPE2023

Endocrine Late Effects In Survival Children With High-Risk Neuroblastoma From Italian Tertiary Hospital

Mirra Giulia , Deodati Annalisa , Ubertini Graziamaria , Elisa Amodeo Maria , Antonietta De Ioris Maria , Mastronuzzi Angela , Cavallo Federica , Grossi Armando

Background: The treatment of high-risk neuroblastoma still represents a clinical challenge in pediatric oncology. About 50% of children survive after a multimodal treatment based on conventional and high dose chemotherapy, surgery, radiotherapy, differentiating treatment and immunotherapy.Aim: To evaluate endocrine long-term sequels in a pediatric cohort with high-risk neuroblastoma.Patient...

hrp0095fc8.4 | Diabetes and Insulin | ESPE2022

Unravelling environmental and genetic determinants of glycaemic control in children and young adults with Type 1 Diabetes

Robi Antonietta , Catamo Eulalia , Tinti Davide , Dovc Klemen , Tonno Raffaella Di , Barbi Egidio , Bonfanti Riccardo , Franceschi Roberto , Rabbone Ivana , Battelino Tadej , Tornese Gianluca

Achieving adequate glycaemic control in children with type 1 diabetes (T1D) is essential to reduce incidence and progression of microvascular and macrovascular complications. However, factors that influence glycaemic control remain to be understood. The present study aimed to evaluate clinical, personal, genetic and eating behaviour characteristics underlying glycaemic control in T1D. 325 T1D individuals aged 6 and 20 years and with at least 1 year of disease duration have bee...

hrp0092p1-300 | Adrenals and HPA Axis (2) | ESPE2019

Growth Trajectory and Final Height in Children with Non Classical Congenital Adrenal Hyperplasia

Wasniewska Malgorzata , Morabito Letteria Anna , Baronio Federico , Einaudi Silvia , Salerno Maria Carolina , Bizzarri Carla , Russo Gianni , Chiarito Mariangela , Grandone Anna , Guazzarotti Laura , Spinuzza Antonietta , Di Carlo Silvia , Ortolano Rita , Balsamo Antonio , Abrigo Enrica , Ferroli Barbara Baldini , Alibrandi Angela , Capalbo Donatella , Faienza Maria Felicia

Background: Subjects with non classical congenital adrenal hyperplasia (NCCAH) often present an increased growth velocity secondary to elevation of adrenal androgens that promote early bone maturation and compromise final height (FH). The aim of the study was to analyze prognostic factors affecting growth trajectory and FH in children with NCCAH.Design: retrospective, multicentric studyStud...