hrp0098p3-52 | Diabetes and Insulin | ESPE2024

Impact of clinical parameters and glycemic control on microalbuminuria levels in children and youth with type 1 diabetes

Asmae Touzani , Layachi Chabraoui , Imane Zineb , Naim a Bennani , Samah Amhager , Yamna Kriouile , Ahmed Gaouzi

Diabetic nephropathy is the leading cause of chronic renal failure. Poor metabolic control exposes the patient to multiple chronic complications, the most serious of which is diabetic nephropathy. This complication is the leading cause of chronic renal failure.Aims: the main aimof our work is to assess the frequency of nephropathy in diabetic children and to study the impact of clinical parameters and metabolic control on microalbuminuri...

hrp0098p3-83 | Fat, Metabolism and Obesity | ESPE2024

The Relation between Obesity and Thyroid Function in Children and Adolescents

Hamed Noor , Soliman Ashraf , Sabt Amal , Alaaraj Nada , Ahmed Shayma , Alyafei Fawzia

Introduction: The prevalence of obesity in children and adolescents is increasing globally, prompting investigations into its effects on various health parameters, including thyroid function.Aim of the Review: To elucidate the relationship between obesity and thyroid function in the pediatric population through a review of recent studies.Review Results: Analysis of studies involvin...

hrp0098p3-128 | GH and IGFs | ESPE2024

Enhancing Diagnostic Accuracy in Growth Hormone Deficiency: A Comparative Analysis of Sex Steroid Priming in Pediatric Short Stature

Alyafei Fawzia , Soliman Ashraf , Qusad Mohamed , Hamed Noor , Alaaraj Nada , Ahmed Shayma , Elsayed Nagwa , Elsiddig Sohair

Introduction: This study presents a comparative analysis of the efficacy of sex steroid priming in enhancing growth hormone (GH) responses in short stature children undergoing GH stimulation tests.Methods: A randomized study encompassed a cohort of 40 children, divided into two groups: "With Priming" and "Without Priming". The primed group exhibited a higher peak GH response (6.53) compared to the non...

hrp0098p3-146 | Growth and Syndromes | ESPE2024

The Impact of Growth Hormone Therapy on Glucose Metabolism in Individuals with Turner Syndrome: A Comprehensive Review

Soliman Ashraf , Alyafei Fawzia , Alaaraj Nada , Hamed Noor , Ahmed shayma , Sabt Amal

Introduction: Growth hormone (GH) therapy in Turner Syndrome (TS) affects growth and glucose metabolism.Methods: Reviewed studies focused on GH therapy's impact on glucose metabolism in TS, selecting those with clear outcomes and sufficient sample sizes.Results: The effects of GH therapy on glucose metabolism in TS vary, with studies indicating both potential risks and benefit...

hrp0098p3-221 | Pituitary, Neuroendocrinology and Puberty | ESPE2024

Etiology of precocious puberty, 8 years study in a Pediatric endocrine Center in Annaba, Algeria

Selim Nihad , Abdelaziz Foued , Chebini Yahia , Sehab Hasna , Lotfi Boustil Ahmed , Bouchair Nadira

Introduction: Precocious puberty, is the development of sexual characteristics occurring before the age of 8 in girls and 9 years in boys, it is a reason for consultation which is becoming frequent, the etiologies are numerous, it Central forms mainly act by early activation of hypothalamic-pituitary-gonadal (HPG) axis which can be idiopathic or secondary to congenital or acquired lesions, rarely the peripheral origin can be the cause.<s...

hrp0098p3-247 | Thyroid | ESPE2024

The Complex Relationship Between Thyroxine Therapy and Growth Outcomes in Pediatric Hypothyroidism

Soliman Ashraf , Alaaraj Nada , Sabt Amal , Hamed Noor , Ahmed Shayma , Alyafei Fawzia

Introduction: Managing pediatric hypothyroidism with thyroxine therapy is crucial for children's growth and development. This presents a synthesized overview of the relationship between thyroxine therapy and growth outcomes in children with congenital and acquired hypothyroidism.Methods: A literature review from 1987 to 2013 was conducted, selecting studies on thyroxine therapy's effects on linear growth, cogni...

hrp0098p3-248 | Thyroid | ESPE2024

The Natural Course of Subclinical Hypothyroidism in Children and Adolescents: A Comprehensive Review

Alaaraj Nada , Soliman Ashraf , Alyafei Fawzia , Hamed Noor , Ahmed Shayma , Adel Ashraf , Sabt Amal

Introduction: Subclinical hypothyroidism (SH) in children and adolescents is a condition characterized by elevated thyroid-stimulating hormone (TSH) levels with normal serum free thyroxine (T4). The clinical significance and natural course of SH remain subjects of debate, necessitating a review of the literature to guide management decisions.Methods: This review analyzed ten studies, encompassing both observational cohor...

hrp0098p3-250 | Thyroid | ESPE2024

Thyroxine's Role in Growth and Development: A Review of Clinical Effects

Alaaraj Nada , Soliman Ashraf , Sabt Amal , Adel Ashraf , Hamed Noor , Ahmed Shayma , Alyafei Fawzia

Background: Thyroxine (T4) is critical in regulating growth and developmental processes. This review synthesizes 20 studies to examine thyroxine's effects on linear growth and development.Methods: A comprehensive review of the last two decades' research articles was conducted, selecting studies that examined thyroxine therapy on growth, development, and metabolic regulation in hypothyroid pediatric populations....

hrp0098p3-252 | Thyroid | ESPE2024

Impact of Subclinical Hypothyroidism on Pediatric Health: A Summary of Findings

Soliman Ashraf , Alaaraj Nada , Sabt Amal , Hamed Noor , Ahmed Shayma , Alyafei Fawzia

Objective: To synthesize evidence on subclinical hypothyroidism (SH) in children, focusing on prevalence, diagnostics, treatment, and progression.Methods: Review of 28 studies including observational cohorts and clinical trials on pediatric SH.Results: SH in children is associated with increased risks of obesity, metabolic syndrome, non-alcoholic fatty liver disease (NAFLD) due to ...

hrp0098p3-299 | Late Breaking | ESPE2024

Coexistence of Autoimmune Disorders in children newly diagnosed with Type 1 Diabetes Mellitus

Selim Nihad , Abdelaziz Foued , Chebini Yahia , Lotfi Boustil Ahmed , Bouchair Nadira

Introduction: Children with type 1 diabetes are at significant risk of developing autoimmune diseases. The international consensus of ISPAD 2022 updated the modalities and pace of screening for the latter. Our goal is to determine the frequency of autoimmune disorders at the time of diagnosis of type 1 diabetes in our department.Materials and Methods: This is a screening for autoimmune thyroiditis and celiac disease in a...