ESPE Abstracts

Objective: Studies contain evidence that anemia in diabetic patients may lead to the development of microvascular and macrovascular complications by causing hypoxia and oxidative stress in peripheral tissues. In this study, we aimed to determine the frequency and risk factors of anemia in children with type 1 DM.Material and Methods: The study group included 82 children with Type 1 DM aged between 1 and 18 years with dis...

Background: Insulin resistance is predominantly associated with obesity. The euglycemic hyperinsulinemic clamp test, the gold standard for diagnosis of insulin resistance, has limited practical application. Although oral glucose tolerance test (OGTT) is generally used instead, there remains a need for more practical methods in outpatient clinics.Aim: The objective of this study is to assess the outcomes of the OGTT in no...

Objective: Our goal was to identify the etiological distribution of our hypoglycemia-diagnosed patients, who presented to pediatric clinics with a variety of symptoms.Materials and Methods: We conducted the study by retrospectively examining recoded data from patients who applied to pediatric emergency services, pediatric outpatient clinics, pediatric metabolism, and endocrinology outpatient clinics between 2015 and 2021...

Objective: Our goal is to determine the impact of bullying on the general physical and emotional health (anxiety and depression) of children with short stature.Method: From September 2020 to December 2020, we conducted a prospective cross-sectional and descriptive study, comparing children aged between 8 and 18 years diagnosed with short stature at a tertiary care Education and Research Hospital, a pediatric endocrinolog...

Aim: This study aims to evaluate the comparative effects of the Minimed 780G system initiated at the time of diagnosis and subcutaneous insulin therapy with continuous glucose monitoring (CGM) systems also initiated at the time of diagnosis on metabolic control and CGM metrics.Methods: We enrolled 8 participants who started using the Minimed780G and 7 participants who started using continuous glucose monitoring (CGM) + m...

Introduction: Autoimmune polyendocrinopathy type 1 (APECED) is an autosomal recessive disease caused by loss of function mutations of autoimmune regulatory (AIRE) gene. Characteristically, early onset ectodermal dysplasia, mucocutaneus candidiasis is followed by hypoparathyroidism and primary adrenal insufficiency usually within the first two decades. Although clinical features may be variable, recently, it is suggested that population characteristics and natu...

Background: Cigarette contains more than 4,000 toxins and is suspected of having endocrine-disrupting properties. Anogenital distance (AGD) is an important biomarker of fetal androgen exposure and intrauterine masculinization. There are limited number of studies examining whether AGD is affected by prenatal smoke-exposure. The aim of this study is to investigate the effects of maternal smoking during pregnancy on newborn infants' AGD.<p class="abstext"...

Background: Resistance to thyroid hormone (RTH) is an inherited syndrome characterized by reduced sensitivity of target tissues to thyroid hormone.Objective and hypotheses: We describe the clinical, biochemical data and mutation analysis of two patients and their families with (RTH).Method: We conducted clinical studies and genetic analysis of these two patients and their families.Results: First patient refer...

Background: Wolcott-Rallison syndrome (WRS) is a rare, autosomal recessive disease and characterized by early-onset diabetes, spondyloepiphyseal dysplasia, short stature, osteopenia, acute liver failure, and neurological deficit. It results from mutation in a gene of the eukaryotic translation initiation factor 2-α kinase 3 (EIF2AK3).Objective and hypotheses: We report two WRS patients diagnosed in infantile period.Me...

Background: Early tooth loss could be the consequence of the local or systemic diseases. We present an odontohypophosphatasia case with otosomal dominant mutation in ALPL gene.Objective and hypotheses: We report a case with odontohypophosphatasia and his family investigation.Method: Three-years-old boy admitted to our pediatric endocrinology clinic with toothloss without any other dental or gingival disease. His serum levels calciu...