ESPE Abstracts

Background: Primary hyperparathyroidism is a rare cause of persistent hypercalcemia in children and adolescents, with parathyroid adenoma being the most common underlying etiology. We are reporting a case of primary hyperparathyroidism due to parathyroid adenoma in an adolescent Pakistani girl with an unusual presentation of difficulty in walking due lower limb deformity (bilateral genu valgum).Case summary: A 13-year-ol...

Background: Few studies have investigated the association between the development and progression of diabetic retinopathy and autoimmune processes resulting from HLA genotype and the relationship of these genes with islet autoantibody status.Objective: This study explored how serum diabetes autoantibodies are related to the development of early diabetic retinopathy (EDR) in children with type 1 diabetes mellitus (T1DM).<...

Background: Growth patterns in early childhood have profound implications for long-term health outcomes. This study aim ed to compare the growth trajectories of Small for Gestational Age (SGA) and Appropriate for Gestational Age (AGA) preterm infants over the first 60 months of life.Methods: A longitudinal analysis of Z-scores for weight-for-age (WAZ), length-for-age (LAZ), and weight-for-length (WLZ) was conducted on pr...

Background: Small for Gestational Age (SGA) infants, characterized by a birth weight below the 10th percentile for their gestational age, are susceptible to growth challenges. This longitudinal study investigates the postnatal growth of 10 SGA infants with birth weights under 1.5 kg, tracking their Weight-for-Age Z-score (WAZ), Length-for-Age Z-score (LAZ), and Weight-for-Length Z-score (WLZ) for five years.Methods: This...

Background: Growth monitoring of Appropriate for Gestational Age (AGA) preterm infants is critical for the assessment of postnatal developmental progress and health outcomes. This study aims to delineate the postnatal growth patterns of AGA preterm infants with birth weights less than 1.5 kilograms, using Z-scores for length-for-age (LAZ), weight-for-age (WAZ), weight-for-length (WLZ), and head circumference-for-age (HCZ) over the first 60 months of life.<...

Background: Understanding the growth trajectories of preterm Appropriate for Gestational Age (AGA) infants with birth weights under 1.5 kg is crucial for optimizing their long-term health outcomes. This study explores the correlations between various growth parameters over five years to identify predictive markers for future growth.Methods: A longitudinal cohort study was conducted on preterm AGA infants (n = 50...

Background: Familial Hypercholesterolemia (FH) increases the risk of atherosclerosis, leading to early cardiovascular disease (CVD) and death at a younger age. Therefore, this study aims to describe the clinical characteristics of FH patients, assess the outcome of adopting reverse cascade screening, and describe the complications and rate of mortality in FH cases followed at our center.Methods & Materials: This is a...

Background: Caregivers of patients with Bardet Biedl syndrome (BBS) face substantial burden from highly prevalent features of the disease, namely hyperphagia, or uncontrollable hunger, and obesity. However, the burden experienced by caregivers of individuals with BBS is not well characterized.Methods: A multicountry cross-sectional survey of caregivers of individuals with BBS was conducted to quantify the burden experien...

Background: Hyperphagia, or pathologic insatiable hunger, and early-onset obesity are prevalent clinical features of Bardet-Biedl syndrome (BBS), a rare genetic disorder. While hyperphagia and obesity have broad impacts on individuals with BBS and their caregivers, the extent of this burden is not well characterized.Methods: This multicountry cross-sectional survey of caregivers of individuals with BBS was conducted to q...

Introduction: Because of the associations and links between abnormal placental weight and both fetal and maternal disorders, it is important to have the national normal standard for placental weight as a normality reference.Aims: To find out the national placental weight standards for babies born between 37th and 43rd weeks of gestation in all groups of males and females babies born AGA, SGA, and LGA.<p class="abstex...