hrp0092rfc7.3 | Diabetes and Insulin Session 2 | ESPE2019

Osteopontin as an Early Urinary Marker of Diabetic Nephropathy in Adolescents with Type 1 Diabetes Mellitus

Ibrahim Amany , Soliman Hend , Abdullatif Mona , Sabry Aly

Introduction: Patients with type 1 diabetes (T1D) have a higher rate of morbidity and mortality compared with the general population, which varies across countries. Diabetic nephropathy (DN) is a common and serious complication of T1D. Osteopontin (OPN) is a calcium binding phosphoprotein that is expressed in glomerular basement membrane. OPN can be a potential marker of vasculopathy and subclinical atherosclerosis and hence a predictor of DN in T1D patients. ...

hrp0084p3-582 | Adrenals | ESPE2015

Rapid Molecular Diagnosis of CAH by Strip Hybridisation Assay in DEMPU

El-Mougy Fatma , Hafez Mona , Atty Sahar Abdel , Ibrahim Amany , Mehawed Hend , Musa Noha , Ekladious Sherif , Elsharkawy Marwa , Abdullatif Mona , Afif Alaa , Baz Heba El

Background: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder in which more than 90% of CAH cases are caused by mutations of the 21-hydroxylase (CYP21A2) gene.Objective and hypotheses: To determine the mutational spectrum in Egyptian CAH patients attending Diabetes Endocrine and Metabolism Pediatric Unit (DEMPU) including family members of CAH patients.Method: The use of reverse hybridization assay for the mol...