hrp0084p1-76 | Fat | ESPE2015

Endothelial Progenitor Cells in Obese Non-Diabetic Children and Adolescents: Relations to Some Metabolic Parameters, Echocardiographic Parameters and Tissue Doppler Imaging

Ahmed Alaa , Youssef Omneya , Thabet Botheina

Background: Endothelial progenitor cells (EPCs) are involved in the regeneration of the endothelial lining following blood vessel injury. The reduction in the number of EPCs was postulated to be associated with the initiation and progression of cardiovascular disease.Objective and hypotheses: This study aimed at exploration of the number of EPCs in obese non-diabetic children and adolescents and their relation to the fasting lipid levels, fasting glucose...

hrp0098p2-257 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2024

Clinical and Laboratory Characteristics of Children with Congenital Adrenal Hyperplasia (CAH): A Comparative Study of Hypertensive and Normotensive Patients

Elsayed Shayma , Tawfeek Soliman Ashraf , Elawwa Ahmed , Alaa ElDin Thabet Mohamed , Marzouk Iman , Elneely Dalia , Diab Dina

Background: Hypertension is a recognized complication in children with Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency, treated with glucocorticoids and mineralocorticoids. This study aims to compare the clinical and laboratory characteristics of children with CAH who developed hypertension with those who maintained normal blood pressure (BP) over a treatment course.Methods: This retrospective cohor...

hrp0098p2-258 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2024

Impact of Precocious Puberty on Clinical Management in Pediatric Patients with Congenital Adrenal Hyperplasia

Elsayed Shayma , Taweek Soliman Ashraf , Elawwa Ahmed , Alaa Eldin Thabet Mohamed , Marzouk Iman , Elneely Dalia , Diab Dina

Background: Congenital Adrenal Hyperplasia (CAH) is a complex endocrine condition with varying presentations, one of which includes precocious puberty. Understanding how precocious puberty affects clinical parameters in pediatric CAH patients is crucial for optimizing management strategies.Methods: This study conducted a comprehensive statistical analysis comparing pediatric CAH patients with precocious puberty (n</e...