hrp0098p1-39 | Fat, Metabolism and Obesity 1 | ESPE2024

The Effect of Excessive Fructose (Corn Syrup) Consumption on Insulin resistance, Lipid Profile and Lipid Peroxidation

Anil Korkmaz Huseyin , Aktug Huseyin , Yavasoglu Altug , Erbas Oytun

Aim: This experimental study is to investigate the effects of excessive fructose consumption on body weight, omental fat, insulin resistance, lipid profile and lipid peroxidation.Materials-Methods: In this study, 18 mature, albino, male Sprague Dawley rats (aged 8 weeks, weighing 200–220 g) were included in our study. They were fed ad libitum, housed in pairs in steel cages, and kept in a temperature-controlled env...

hrp0089p2-p123 | Fat, Metabolism and Obesity P2 | ESPE2018

Allopurinol Ameliorates Non-Alcoholic Fatty Liver Disease in Rats

Anil Korkmaz Huseyin , Aktug Huseyin , Atila Dincer , Barisik Vatan , Arslan Nur , Erbas Oytun

Background: Hyperuricemia has been found to be associated with non-alcoholic fatty liver disease (NAFLD).Aim: The aim of this study was to evaluate whether allopurinol affects the course of experimental NAFLD in rats.Study Design: Mature, albino Sprague Dawley rats were fed water containing 30% fructose without ethanol for up to 8 weeks. After demonstration of steatosis in the 8th week, either allopurinol or saline was administered...