ESPE Abstracts

Prader–Willi syndrome (PWS) is a rare genetic disorder resulting from lack of expression of the paternally derived chromosome 15q11–13, associated with several complications, including pubertal disorders, short stature, hyperphagia, obesity, glucose metabolism abnormalities, scoliosis, obstructive sleep apnea syndrome (OSAS) and behavioral problems. We report the case of a girl affected by PWS who presented at the age of 5.9 with premature pubarche, accelerated lin...

Introduction: Asprosin is a new discovered adipokine involved in the regulation of appetite, glucose, and energy homeostasis. The aim of our study was to evaluate asprosin serum levels in children and adults affected with Prader-Willi Syndrome (PWS), and to compare with hyperphagia questionnaire (HFQ), anthropometric and metabolic parameters.Methods: This cross-sectional study included 118 PWS subjects (88 children, mean...