ESPE Abstracts

Background: Celiac disease is an important association of type 1 diabetes with significant impact on growth and glycemic control. Identification of the disease in asymptomatic subjects highlights the need for celiac screening in type 1 diabetes. Disparity in screening guidelines suggests the need for exploration of time trend and predictors of the association.Objective: To estimate the time trend, prevalence and predicto...

Background: Aromatase deficiency has been associated with disordered sexual development in infancy and delayed puberty later. The condition responds to estradiol treatment with normalization of gonadotropin levels and pubertal development. We report a girl with a novel Aromatase mutation with persistently elevated gonadotropin levels despite adequate estrogen treatment.Case report: This thirteen and a half year old girl ...

Background: The lack of systematic evaluation of growth disorders results in unnecessary workup for physiological causes while missing pathological causes. We have developed Bone-age assisted interpretation of growth (BIG), a web-based tool that provides guidance for diagnosis and management for children and adolescents with growth concerns.Aim: To develop and validate BIG in growth disorders.<stro...

Introduction: Lack of systematic evaluation for pubertal disorders leads to unnecessary work-up and treatment in physiological cases while missing out pathological cases. Developing a point-of-care tool to allow systematic evaluation of such cases is desirable as it allows early identification and referral.Aim: To develop a web-based tool to guide evaluation in children presenting with pubertal disorders.<p class="ab...

Introduction: Isolated micropenis is a common presentation to a pediatric endocrine clinic causing significant parental anxiety. Little is known about the dose and duration of treatment as well as long-term outcomes in such children.Aim: To identify the course and predictors of puberty in boys with isolated micropenis.Method: Records of 102 boys presenting with isolated micropenis ...

Background: The assessment of childhood obesity involves rational use of diagnostic tests in individuals with physiological causes while not missing pathologies. We have developed obesity interpreter, a mobile application that provides individualized guidance regarding the workup of children and adolescents.Aim: To validate the diagnostic accuracy of mobile application in the evaluation of children and adolescents with o...

Background: Assessment of pubertal disorders is challenging for the pediatricians causing unnecessary evaluation on one hand while missing pathology on the other. The paucity of pediatric endocrine centers further adds to the problem in resource poor settings. We have developed puberty interpreter, a mobile application that provides instantaneous guidance regarding diagnosis and management of children and adolescents with concern for pubertal disorders based o...

Background: Atypical genitalia represents an important medical and social emergency. Lack of training in Pediatric Endocrinology and restricted access to Pediatric Endocrinologists makes developing tools for point-of-care guidance for children with atypical genitalia desirable.Objective: To develop and validate a point-of-care mobile application to guide the assessment of children with atypical genitalia.<p class="ab...