hrp0086p2-p329 | Diabetes P2 | ESPE2016

The Prevalence of Dyslipidemia and Associated Factors in Children and Adolescent with Type I Diabetes

Bulut Tuba , Demirel Fatma , Metin Ayşe

Background: Dyslipidemia increases the frequency and severity of micro- and macro-vascular complications of type 1 diabetes.Objective and hypotheses: The present study aims to determine the prevalence of dyslipidemia and its association with clinical and laboratory findings in diabetic children and adolescents.Methods: The study included 202 children and adolescents with type 1 diabetes. Demographic data and laboratory findings wer...

hrp0089p3-p095 | Diabetes & Insulin P3 | ESPE2018

The Relationship between Serum Levels of C-Peptide and the Age, BMI, and Insülin Doses in Reply to: Newly Diagnosed Type 1 Diabetic Children

Karaguzel Gulay , Usta Deniz , Tavaci Ayşegul , Taniş Mustafa , Beyhun Ercument

Background and aim: C-peptide is an important indicator of endogenous insulin release. Our aim was to investigate the association of serum C-peptide levels with age, BMI and insulin doses in newly diagnosed type 1 diabetic (DM1) children.Metods: The patients with newly diagnosed DM1 were enrolled the study and classified as DM1A and DM1B. Clinical and laboratory findings of all the patients were recorded. Daily insulin doses, BMI and its z score were cal...

hrp0092p2-291 | Thyroid | ESPE2019

Investigation of Oxidative Effect in Saliva and Gingival Groove Fluids in Children with Hashimoto Thyroiditis

Atar Müge , Tan Aykut , Yetkin Ay Zuhal , Atar Müge , Pirgon Özgür

The aim of this study was to determine the periodontal health status in patients with Hashimoto thyroiditis (HT) and investigate the gingival groove fluid and saline oxidative stress parameters in order to demonstrate their relationship.Method: 30 patients between the ages of 11-17 years and 30 healthy volunteers aged between 10-17 years were included in the study. Serum tT4, TSH, anti-TPO, glucose, insulin, ALT, triglyceride, total chol...

hrp0094p1-53 | Bone B | ESPE2021

Growth and Puberty in Patients with Osteogenesis Imperfecta

Pınar Ozturk Ayşe , Ozturan Esin Karakılıc , Poyrazoğlu Şukran , Baş Firdevs , Darendeliler Feyza ,

Aim: Osteogenesis imperfecta (OI) is a genetic disease of extracellular matrix presenting with varying degrees of skeletal fragility. The study aims to evaluate growth and pubertal characteristics of 83 patients with OI.Materials and methods: Patients were classified according to Sillence clinical classification criteria. Demographic data, clinical findings, growth and pubertal characteristics were recorded from medical charts, retrospec...

hrp0094p1-128 | Growth A | ESPE2021

Evaluation of Persistent Short Stature in Children Born Small for Gestational Age without Catch-up Growth

Pınar Ozturk Ayşe , Ozturan Esin Karakılıc , Poyrazoğlu Şukran , Baş Firdevs , Darendeliler Feyza ,

Aim: The majority of children born small for gestational age (SGA) demonstrate spontaneous catch-up growth in height by the age of two years; however, approximately 10-15% of SGA newborns are at risk of having subnormal growth and persistent short stature (PSS).Method: We evaluated clinical, anthropometric, and laboratory characteristics of the 86 children with PSS who were born SGA.Results...

hrp0092p1-117 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

The Role of Rat Hypothalamus Kisspeptin, Neurokinin and their respective Receptors in the Prolactin-Infertility Interaction

Isik Eylul Akbal , USLU Inayet Nur , AY Gulsevinc , CETINEL Nesrin , COMERTPAY Gamze , OKSUZ Hale , BARC Deniz , AKILLIOGLU Kubra , TOPALOGLU Ali Kemal , YILMAZ Mehmet Bertan

Aim: In this study, we investigated whether there was a relationship between prolactin hormone (PRL), whose excess levels lead to infertility, and expression of Kisspeptin (Kiss1), Neurokinin (Tac2) and their respective Receptors.Material and Methods: In our study, 12-16 weeks old 40 female Wistar Albino rats were classified into three groups; control group (n=10), physiological saline (SF) (n=1...

hrp0092p2-137 | Fat, Metabolism and Obesity | ESPE2019

Clinical Characteristics and Response to Growth Hormone Treatment in Patients with Prader-Willi Syndrome

Evliyaoglu Olcay , Dagdeviren Cakir Aydilek , Bas Firdevs , Akin Onur , Siklar Zeynep , Özcabi Bahar , Berberoglu Merih , Kardelen Asli Derya , Bayramoglu Elvan , Poyrazoglu Sükran , Aydin Murat , Ergül Türel Ayça , Göksen Damla , Bolu Semih , Aycan Zehra , Tüysüz Beyhan , Ercan Oya

Introduction and aim: Prader-Willi syndrome(PWS), is a genetic disorder caused by the absence of paternal genes located on chromosome 15q11.2-q13. In this multi-central study; patients with PWS were followed for 2 years. Initial clinical and laboratory findings, growth hormone(GH) treatments and their responses were evaluated.Patients and Methods: 54 patients from 10 pediatric endocrine centers were involved and data was...

hrp0094p2-423 | Sex differentiation, gonads and gynaecology or sex endocrinology | ESPE2021

Diagnostic dilemma in a patient with central precocious puberty: Ovarian steroid cell tumor

Balki Hanife Gül , Ata Aysun , Karayazılı Ayşe Merve , Serin Gürdeniz , Koç Gonca , Özdemir Necmettin , Çelik Ahmet , Özen Samim , Gökşen Damla , Darcan Şükran

Ovarian steroid cell tumors (OSCT) are rare sex cord stromal tumors of the ovary and comprise <0.1% of all ovarian tumors. We herein report a case of an OSCT in a 9 year old girl patient who presented with central puberty preocious unresponsive to gonadotrophine relasing hormon analog (GnRH) therapy. A 9 year old girl presented with breast development noticed 4 months ago and menarche 3 months ago. Her height was 141,5 cm (+1,3 SDS), body weight was 35.4 kg (+0.9 SDS) and...