hrp0084p3-631 | Autoimmune | ESPE2015
Balsamo Claudia
, Porcu Eleonora
, Baronio Federico
, Forchielli Luisa
, Bazzocchi Antonia
, Mazzanti Laura
, Cassio Alessandra
Background: Autoimmune polyendocrine syndrome type 2 (APS2) is a complex disorder characterised by the obligatory occurrence of Addison disease in combination with thyroid autoimmune disorder and/or type 1 diabetes. APS 2 is the most common autoimmune polyendocrine syndrome and is primarily manifest in adult age. Premature ovarian failure (POF) is defined as sustained amenorrhea before the age of 40 years, FSH levels higher than 40 UI/l and hypoestrogenism associated with infe...