hrp0086p1-p595 | Growth P1 | ESPE2016
, Eggermann Thomas
, Weber Karin
, Schweizer Roland
Background: Recently we described a family with several members having intrauterine and postnatal growth failure as well as signs of SilverRussell syndrome (SRS) who carried a heterozygote nonsense mutation of IGF2. The patients had low IGF-II serum levels, but normal IGF-I serum levels.Objective and hypotheses: We aimed to estimate the diagnostic value of the IGF-II, IGF-I and IGFBP-3 measurements in the assessment of children with SRS.<p clas...