hrp0089p2-p179 | Fat, Metabolism and Obesity P2 | ESPE2018

Body Composition Parameters, Systemic Inflammation and Metabolic Syndrome Manifestations in Children and Adolescents

Christaki Eirini , Pervanidou Panagiota , Bastaki Despoina , Valavani Eleni , Kanaka-Gantenbein Christina , Boschiero Dario , George Chrousos

Introduction: Increased adiposity has been associated with smoldering systemic inflammation and metabolic syndrome manifestations, leading to further morbidity by increasing the risk for type 2 diabetes mellitus and cardiovascular disease in adults. Similar analyses have not been performed systematically in children and adolescents.Hypothesis: This study investigates the interrelations between body composition parameters and indices of inflammation and m...

hrp0084p2-427 | GH & IGF | ESPE2015

rhGH Replacement Therapy Ameliorates Body Composition Substantially but has No Effect in the Quality of Life in Adolescents with GH deficiency – A Cross-Sectional Study

Stefanaki Charikleia , Paltoglou George , Bacopoulou Flora , Boschiero Dario , Chrousos George P

Background: GH is fundamental in skeletal growth during puberty, however detailed studies of body composition analyses in adolescents with GH deficiency on GH therapy are scarce. Moreover, there are few studies on the psychologic aspects of hrGH therapy in this population.Objective and hypotheses: In this case-control study, we investigated differences in body composition based on bio-impedance measurements between adolescents with idiopathic GH deficien...

hrp0086p1-p478 | Fat Metabolism and Obesity P1 | ESPE2016

BMI Correlates Positively with Hair Cortisol, whereas Excessive Body Fat Correlates Positively with Hair Cortisol: Salivary Cortisol and Fasting Insulin Concentrations in Prepubertal Girls

Christaki Eirini , Papafotiou Chrysanthe , Bastaki Despoina , van den Akker Erica L.T. , Wester Vincent L. , Boschiero Dario , Pervanidou Panagiota , Kanaka-Gantenbein Christina , Chrousos George

Background: Chronic stress and increased adiposity have been associated with each other in children. Further studies are needed, however, to evaluate both the directionality of this association and the mediating metabolic mechanisms.Objective and hypotheses: This study investigates the interrelations between BMI, body composition parameters, indices of the stress response, such as hair and salivary cortisol levels, and, metabolic mediators, such as insul...