hrp0089p2-p312 | Pituitary, Neuroendocrinology and Puberty P2 | ESPE2018

Ultrasound Assessment of Pubertal Breast Development: Intra- and Inter-Observer Agreement

Bruserud Ingvild , Mathieu Roelants , Oehme Ninnie , Egil Eide Geir , Bjerknes Robert , Rosendahl Karen , Juiliusson Petur

Background: Clinical assessment of pubertal breast development using Tanner staging is subjective. This has led to the introduction of ultrasound, aiming for a more objective analysis. However, information regarding its reliability is lacking.Objective: To examine intra- and inter-observer agreement of breast maturity staging using ultrasound, and to examine the precision of direct measurements of the gland.Materials and methods: F...

hrp0097p1-312 | Growth and Syndromes | ESPE2023

Associations between weight-related anthropometric measurements and occurrence of breast development, pubic hair and menarche

S. Bruserud Ingvild , Roelants Mathieu , B. Júlíusson Peacute;tur

Background: The timing of puberty is influenced by different factors, one of which is body composition. The aim of the current study was to investigate if anthropometric indicators of body composition, body mass index(BMI), waist circumference(WC), subscapular skinfold(SSF) and body fat percentage(BF%) were differentially associated with occurrence of breast development, pubic hair and menarche in Norwegian girls.Methods:</strong...

hrp0089p2-p304 | Pituitary, Neuroendocrinology and Puberty P2 | ESPE2018

Ultrasound-Based Measurements of Testicular Volume in 6–16 Year Old Boys: Intra- and Inter-Observer Agreement and Comparison with Prader Orchidometry

Oehme Ninnie , Roelants Mathieu , Bruserud Ingvild Saervold , Egil Eide Geir , Bjerknes Robert , Rosendahl Karen , Juliusson Petur B

Background: Prader orchidometry has been the standard method for evaluating testicular size. As this technique is subjective and tends to overestimate the testicular volume, ultrasound has been proposed as a more reliable method.Objective: To evaluate the intra- and inter-observer agreement of ultrasound measurements of testicular volume and comparison with Prader orchidometry.Materials and methods: Length, width and depth of the r...

hrp0089p1-p230 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P1 | ESPE2018

Testicular Ultrasound Measurements to Stratify Pituitary-Gonadal Hormone References in a Cross-Sectional Norwegian Study of Male Puberty

Madsen Andre , Ninnie Oehme , Bruserud Ingvild , Roelants Mathieu , Egil Eide Geir , Sagen Jorn , Mellgren Gunnar , Juliusson Petur

Background: Recent research has demonstrated earlier testicular and pubertal development in Western boys. New ultrasound-based references of testicular growth in Norwegian boys are now available. Population specific references for FSH, LH and sex steroid hormones have not been previously available in Norwegian children and adolescents.Objective and hypotheses: We aimed to provide an elaborate description of pubertal development in a sample of contemporar...

hrp0097rfc6.3 | Pituitary, neuroendocrinology and puberty 1 | ESPE2023

Exposure to Per- and Polyfluoroalkyl Substances and Pubertal Assessment by Ultrasound in Norwegian Boys and Girls: Data from the Bergen Growth Study 2

Halsør Forthun Ingvild , Roelants Mathieu , Småstuen Haug Line , Katrine Knutsen Helle , Særvold Bruserud Ingvild , Benedikt Juliusson Petur

Background and aim: Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals found in everyday consumer products. These chemicals are considered endocrine disruptive. However, their effect on pubertal onset and development is still unclear. The aim of the current study was therefore to explore the relationship between PFAS exposure and pubertal development using novel objective pubertal phenotyping, e.g., ultrasound-determined testicular v...

hrp0092p1-110 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

References for Testicular Volume Measured by Ultrasound and for Pubic Hair in 6-16 Year-Old Norwegian Boys

Oehme Ninnie B. , Roelants Mathieu , Bruserud Ingvild S. , Madsen André , Eide Geir Egil , Bjerknes Robert , Rosendahl Karen , Júlíusson Pétur B.

Objective: Recent studies have suggested earlier onset of pubertal development in boys. As assessment with orchidometer tends to overestimate true testicular volume (TV), and measurements based on ultrasound (US) have been proposed as a more reliable method, we present US based references in 6-16 year-old Norwegian boys. Our results are compared with data from Europe and the United States (U.S.) in order to establish evidence for an ongoing secular trend in ma...

hrp0092p1-267 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology (1) | ESPE2019

Endocrine Profiling and Association with Ultrasound Measured Testicular Volume and Biometrics in a Cohort of Norwegian Boys

Madsen André , Oehme Ninnie , Bruserud Ingvild , Roelants Mathieu , Sagen Jørn , Mellgren Gunnar , Júlíusson Pétur

Introduction: Male puberty is initiated by endocrine signaling in the hypothalamic-pituitary axis whereby follicle-stimulating hormone (FSH) and luteinizing hormone (LH) enable testicular maturation and synthesis of testosterone. Recent publications have eluded to overnutrition and obesity as relevant factors that may accelerate the timing of puberty. Attainment of testicular volume (TV) 4 ml measured by Prader orchidometer remains the definition of male puber...