hrp0082p3-d3-750 | Diabetes (4) | ESPE2014

A Case of Type 1 Diabetes Associated with Cerebellar Ataxia: Stiff-Person Syndrome

Kurtoglu Selim , Okdemir Deniz , Hatipoglu Nihal , Akin Leyla , Gul Ulku , Canpolat Mehmet , Kendirci Mustafa

Background: Stiff-person syndrome (SPS) is a rare disorder which is characterized by muscle rigidity, spasm and cerebellar abnormalities. The etiology is not clarified yet. 80% of cases are caused by an autoantibody against GAD that inhibits synthesis of GABA. Other autoimmune diseases such as type 1 diabetes mellitus and thyroiditis are often associated.Aim: To underline the importance of considering SPS in differential diagnosis of patients with type 1...