hrp0086rfc14.6 | Growth : Mechanisms | ESPE2016
Smeets Carolina
, Codd Veryan
, Samani Nilesh
, Hokken-Koelega Anita
Background: Small birth size followed by accelerated weight gain in early life is associated with an increased risk for age-associated diseases, such as cardiovascular disease (CVD) in later life. The underlying causes for this are largely unknown. Leukocyte telomere length (LTL) is a marker of biological age and short LTL is associated with increased CVD-risk. Subjects born small for gestational age (SGA) who remain short are treated with growth hormone (GH) to improve adult ...