hrp0094p2-386 | Pituitary, neuroendocrinology and puberty | ESPE2021

Blood Pressure in Girls with Central Precocious Puberty and GnRH Analog Therapy

Fisch Shvalb Naama , Harani Hadas Alfandary , Davidovits Miriam , Shvalb Nir , Demol Eliaz Sharon , Yackobovitch Gavan Michal , Phillip Moshe , de Vries Liat ,

Objectives: Several case reports describe hypertension (HTN) in children treated with GnRH analogs for central precocious puberty (CPP). However, relevant data on blood pressure (BP) under GnRH analog treatment are scarce. We evaluated BP among girls with idiopathic CPP and early puberty (EP) before, during and after GnRH analog therapy, and examined associations of BP with clinical parameters.Design: A retrospective longitudinal cohort ...