hrp0082p2-d2-544 | Puberty and Neuroendocrinology (1) | ESPE2014

Impact of Being Born Small or Large for Gestational Age on Pubertal Onset and Progression

Loredana Marcovecchio M , Di Giovanni Ilaria , de Giorgis Tommaso , Polidori Nella , Chiavaroli Valentina , Mohn Angelika

Background: Perinatal factors seem to influence the onset of puberty. There is some evidence suggesting that being born small for gestational age (SGA) is associated with early puberty, whereas the effect of large size at birth on timing of puberty is not clear.Objective and hypotheses: To evaluate the timing of puberty in children born SGA and large for gestational age (LGA) compared to children born appropriate for gestational age (AGA).<p class="a...

hrp0082lbp-d3-1003 | (1) | ESPE2014

Increasing Incidence of Infants Born Small and Large for Gestational Age Over 20 Years

Chiavaroli Valentina , Castorani Valeria , Guidone Paola , Di Giovanni Ilaria , Liberati Marco , Chiarelli Francesco , Mohn Angelika

Background: Infants born small (SGA) and large (LGA) for gestational age have been identified at increased risk of perinatal morbidity and later cardio-metabolic alterations. Nevertheless, the progression over time in incidence of SGA and LGA births is yet to be determined.Objective and hypotheses: To investigate temporal trends in SGA and LGA infants compared to those born appropriate (AGA), and to identify factors potentially associated over a 20-year ...

hrp0084p3-861 | Fat | ESPE2015

Decreased Insulin Sensitivity and Secretion in Obese Youth with High OGTT Derived 1 h Blood Glucose

Loredana M Loredana M , Marisi Elsa , Di Giovanni Ilaria , De Leonibus Chiara , Chiarelli Francesco , Mohn Angelika

Background: Obese adults with normal glucose tolerance (NGT) but 1-h post load glucose (1 hPG)≧155 mg/dl have an increased cardiometabolic risk. In children, preliminary data suggest that 1hPG≧132.5 mg/dl might identify those at higher risk of type 2 diabetes.Objective and hypotheses: To assess whether NGT obese youth with 1hPG ≧132.5 mg/dl (High-NGT) have worse insulin sensitivity and secretion compared to obese youth with 1hPG &#60...