hrp0092p3-275 | Late Breaking Abstracts | ESPE2019

Serum Spexin is Correlated with Lipoprotein(a) and Androgens in Normal-Weight, Overweight and Obese Adolescent Females

Bacopoulou Flora , Apostolaki Despoina , Mantzou Aimilia , Doulgeraki Artemis , Pałasz Artur , Koniari Eleni , Efthymiou Vasiliki

Background: The Spexin gene is considered the most dysregulated in obese human fat with an almost complete absence of expression in obese human fat in comparison with non-obese fat tissues. Limited data from human and animal studies suggest that the novel peptide spexin may potentially impact food intake, weight regulation and body adiposity.Objective: The aim of this study was to compare serum spexin concentrations betw...

hrp0092p3-302 | Late Breaking Abstracts | ESPE2019

Cognitive and Learning Performance of Children and Adolescents Cancer Survivors

Mavrea Kalliopi , Efthymiou Vasiliki , Katsibardi Katerina , Roka Kleoniki , Pons Roser , Kattamis Antonis , Bacopoulou Flora

Objective: The aim of this study was to compare the sociodemographic and cognitive profile, the learning performance and symptoms of attention deficit hyperactivity disorder (ADHD) of children and adolescents survivors of pediatric cancer to those of healthy controls.Methods: Thirty survivors of pediatric cancer and thirty age-matched controls (mean age ± SD 11.7 ± 2.7 years, 46.0% boys, 54.0% girls) we...

hrp0089rfc14.1 | Multisystem Endocrine Disorders | ESPE2018

Psychometric and Psycho-social Profile of Children and Adolescent Survivors of Pediatric Cancer

Bacopoulou Flora , Mavrea Kalliopi , Adamaki Christina , Efthymiou Vasiliki , Katsibardi Katerina , Kattamis Antonis

Objective: The aim of this study was to compare the psychometric and psychosocial profile of children and adolescents survivors of pediatric cancer to that of healthy controls.Methods: Children and adolescents survivors of pediatric cancer, aged 7–17 years, who attended the Hematology-Oncology Unit of the First Department of Pediatrics, and healthy controls who visited the Centre for Adolescent Medicine and UNESCO Chair on Adolescent Health Care of ...

hrp0089p1-p095 | Fat, Metabolism and Obesity P1 | ESPE2018

Variation of Circulating Brain-Derived Neurotrophic Factor According to Gender, Body Mass Index and Metabolic Syndrome Parameters in Adolescents

Bacopoulou Flora , Tsitsimpikou Christina , Mantzou Aimilia , Apostolaki Despoina , Darviri Christina , Efthymiou Vasiliki

Background: Brain-derived neurotrophic factor (BDNF) plays a role in the central regulation of energy balance and has been associated with body mass index (BMI).Objective: The aim of this study was to investigate potential differences in serum BDNF concentrations in adolescents by gender and BMI, as well as possible correlations of circulating BDNF with the adolescentsÂ’ characteristics of metabolic syndrome.Methods: Study part...

hrp0089p2-p134 | Fat, Metabolism and Obesity P2 | ESPE2018

Serum Spexin Concentrations in Adolescent Females with Metabolic Syndrome, Polycystic Ovary Syndrome and Anorexia Nervosa

Bacopoulou Flora , Efthymiou Vasiliki , Apostolaki Despoina , Tsitsimpikou Christina , Tsarouhas Konstantinos , Darviri Christina , Mantzou Aimilia

Background: Spexin is a novel hormone that may potentially impact food intake, weight regulation and body adiposity. Circulating spexin has been associated with obesity and insulin resistance indices in women.Objective: The aim of this study was to determine serum spexin concentrations in adolescent females with metabolic syndrome, with polycystic ovary syndrome (PCOS), with anorexia nervosa as well as in healthy controls, and explore possible relationsh...