hrp0098p2-126 | Fat, Metabolism and Obesity | ESPE2024

First year outcomes in a Paediatric Complications of Excess Weight (CEW) Service

Osman Khadiga , Wright Neil , Ferguson Elspeth

Background: Childhood obesity remains a significant public health concern, with weight management programmes to date only showing limited success. This project aims to evaluate initial first year outcomes for our Complications of Excess Weight (CEW) Service based at our tertiary paediatric centre. Children and young people with significant obesity in our region and referred to the service, receive tier 3 weight management support, including intensive lifestyle...

hrp0095p1-211 | Adrenals and HPA Axis | ESPE2022

Effect of maternal steroid medication prescribed during pregnancy on neonatal adrenal function

Ahmed Aneeq , Hattangadi Ibani , Gopalakrishna Nagapratheek , De Silva Shamani , Elder Charlotte , Ferguson Elspeth

Background: There is limited data supporting concerns that systemic corticosteroids, prescribed in pregnancy for maternal health reasons, can suppress the neonatal Hypothalamic-Pituitary-Adrenal (HPA) axis. Our study aimed to determine if neonates born to mothers on long-term or high dose steroids are at risk of adrenal suppression.Methodology: Neonates who underwent assessment of adrenal function over a seven-year perio...

hrp0098p1-213 | Adrenals and HPA Axis 3 | ESPE2024

Prematurity and low birth weight may be key indicators for a low peak cortisol on neonatal Short Synacthen Tests

Ahmed Aneeq , Hattangadi Ibani , Gopalakrishna Nagapratheek , De Silva Shamani , Elder Charlotte , Ferguson Elspeth

Background: There are multiple indications where evaluation of the Hypothalamic-pituitary-adrenal (HPA) axis in neonates may be considered e.g. hypoglycaemia, hypotension, conjugated hyperbilirubinemia; however permanent neonatal adrenal insufficiency (AI) is rare. Interpretation of results can be challenging due to a paucity of normative reference data in this population. This risks overdiagnosis and unnecessary treatment with corticosteroids leading to the a...