hrp0098fc3.5 | Pituitary, Neuroendocrinology and Puberty 1 | ESPE2024

Screening for First Morning Voided (FMV) Urinary Gonadotropin (Gn) in Children with Normal and Precocious Puberty (PP): A Prospective, Multi-Center, Large-Sample based Study in China

Ye Feng , Chen Ruimin , Yang Yu , Zhang Dongguang , Dong Zhiya , Lu Wenli , Zhu Min , Cheng Xinran , Gou Peng , Ma Huamei , Chen Qiuli , Dong Guoqing , Gong Chunxiu , Luo Feihong , Luo Xiaoping

Background: Clinical use of serum gonadotropins (Gn) test for diagnosis of pubertal disorders is always limited by invasive sampling, requirement of hospital visit, high expense and the feature of pulsatile secretion of Gn. As an alternative, evaluating first morning voided (FMV) urinary Gn (U-Gn) may facilitate non-invasive pubertal assessment.Objective: In this study, we will explore whether FMV U-Gn can predict the ac...