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hrp0097rfc8.2 | Fat, metabolism and obesity 2 | ESPE2023

Acute rise of leptin after five days of dexamethasone and its association with hunger, fat mass, sleep and fatigue, in children with acute lymphoblastic leukemia

van Hulst Annelienke , Verwaaijen Emm , van den Berg Sjoerd , van Litsenburg Raphaele , Grootenhuis Martha , Fiocco Marta , Neggers Sebastian , van den Heuvel-Eibrink Marry , van den Akker Erica

Background & Aims: Children with acute lymphoblastic leukemia (ALL) frequently receive high doses dexamethasone during treatment, which may induce acute side effects. The aims of the current study were to determine the influence of a five-day dexamethasone course on changes in leptin, fat mass, body mass index (BMI), hunger, sleep and fatigue and to explore the associations between these changes.Methods: Pediatric AL...

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hrp0097rfc13.3 | Pituitary, neuroendocrinology and puberty 2 | ESPE2023

Treatment and outcome of the Dutch Childhood Craniopharyngioma Cohort study; first results after centralization of care

van Schaik Jiska , Schouten-van Meeteren Netteke , Vos-Kerkhof Evelien , Janssens Geert , Porro Giorgio , Fiocco Marta , Bakker Boudewijn , Tissing Wim , Hoving Eelco , van Santen Hanneke

Introduction: Childhood craniopharyngioma (cCP) has excellent survival, but quality of life may be severely hampered by hypothalamic dysfunction. We aimed to evaluate treatment and hypothalamic outcomes of a Dutch cCP cohort, and evaluate the effect of centralization of care.Methods: A retrospective cohort study was performed, including cCP patients diagnosed between 2004-2021. Treatment characteristics and hypothalamic ...

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ESPE Abstracts

Acute rise of leptin after five days of dexamethasone and its association with hunger, fat mass, sleep and fatigue, in children with acute lymphoblastic leukemia

Treatment and outcome of the Dutch Childhood Craniopharyngioma Cohort study; first results after centralization of care

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