hrp0082fc12.3 | Obesity | ESPE2014

Increased Resting Energy Expenditure in Girls with Turner Syndrome

Binder Gerhard , Frank Laura , Blumenstock Gunnar , Schweizer Roland

Background: There is no knowledge of the energy metabolism in the presence of X chromosome aneuploidy or structural aberrations. Recently, an abnormal muscle metabolism was observed in girls with Turner syndrome (TS).Objective and Hypotheses: Resting energy expenditure was prospectively estimated by indirect spirometry in 92 short prepubertal girls at the start of GH therapy.Method: The diagnoses were TS (n=23), GH deficie...

hrp0082p2-d2-433 | Growth Hormone (1) | ESPE2014

Comparison of Measured Lean Body Mass (LBMDXA) and Estimated LBMBIA in Children with GH Deficiency

Schweizer Roland , Ziegler Julian , Frank Laura , Binder Gerhard

Background: Long standing GH deficiency (GHD) causes loss of muscle mass. DXA enables the measurement of LBMDXA but is accompanied with a potentially harmful X-ray exposition. BIA measures the electric resistance of the body which correlates with LBM. A comparison of both methods in children with GHD has not been performed yet.Aim: Calculation of a regression formula for LBM using resistance and anthropometry based on LBMDXA in chil...