hrp0098p3-36 | Bone, Growth Plate and Mineral Metabolism | ESPE2024

A 5-year-old girl with severe nutritional rickets mimicking hypophosphatemic rickets (XLH)

Giulia Lambertini Anna , Lumaca Alessandra , Ortolano Rita , Baronio Federico , Zucchini Stefano

The measurement of serum FGF23 plays a pivotal role in the differential diagnosis of patients with hypophosphatemia. However, its interpretation may be difficult in some cases. We report the case of a child with rickets and severe hypophosphatemia, where both intact FGF23 (iFGF23), the active form, and C terminal FGF23 fragments (C-FGF23) were measured.Case report: A 5.7-year-old girl, born at term from first-grade-related Pakistani pare...

hrp0097p1-186 | Thyroid | ESPE2023

Comparison of clinical features, therapy, and disease evolution in a population of children and adolescents with Graves' disease and Type 1 Diabetes compared to Graves' disease alone.

Bernardini Luca , Maltoni Giulio , Cristina Vigone Maria , Franceschi Roberto , Cardinale Giuliana , Mameli Chiara , Piscopo Alessia , Roppolo Rosalia , Savastio Silvia , Ortolani Federica , Randazzo Emioli , Giulia Lambertini Anna , Cassio Alessandra

Introduction: About 25% of children and adolescents with Type 1 Diabetes (T1D) have one or more associated autoimmune conditions. Although Graves' disease (GD) rarely occurs, considering the potential severity of manifestations, an early diagnosis and appropriate treatment are essential. The first line treatment is methimazole, whose use is not free from side effects; therefore, it is important to start with the most appropriate dosage.<p class="abste...