hrp0094p2-2 | Adrenals and HPA Axis | ESPE2021
Sommer Grit
, Abawi Ozair
, Groessl Michael
, Halbsguth Ulrike
, Charmandari Evangelia
, Akker Erika L.T. van den
, Fluck Christa E.
,
Introduction: Steroid profiling in children with congenital adrenal hyperplasia (CAH) is used to monitor the balance between androgen and cortisol metabolites and to decide on the optimal glucocorticoid dosage. Twenty-four hour collection is the gold standard for measurement of steroid metabolites in urine, because steroid production follows a circadian rhythm and is influenced by short-term stress and steroid drugs. For some children, e.g. those who were diap...