ESPE Abstracts

Background: Neoplastic causes of precocious puberty include brain, gonadal, adrenal and germ cell tumors; hepatoblastoma (HB) is only rarely noted [1,2]. HB, is a rare primary hepatic tumor of childhood [3]. It is accompanied by raised levels of alpha-fetoprotein (α-FP). Rarely, beta-human chorionic gonadotropin (β-hCG) levels are elevated, resulting in peripheral precocious puberty (PPP).Clinical Case: We pre...

Objective: To present the spectrum of monogenic obesity presenting to a tertiary children’s hospital in UAEIntroduction: Monogenic obesity is increasingly recognized as a cause of severe early-onset obesity. Monogenic obesity syndromes arise from single gene mutations affecting critical for regulation of body weight and energy balance. Children with monogenic obesity often experience severe, early-onset weight gain...

Background: Neurological outcomes in congenital hypothyroidism can be optimized by timely diagnosis and treatment. In this study, we compared the neurodevelopmental status of children with congenital hypothyroidism with healthy controls.Methods: This cross-sectional study was performed in southern India between 2022 and 2024 after obtaining ethics approval. The neurodevelopmental outcome of 42 congenital hypothyroidism c...

Background: Exposure to intrauterine adrenocortical tumors (IATs) is an exceedingly rare of virilization in females. We present the case of a virilized female infant, born after diagnosis of a maternal adrenocortical tumor, diagnosed in pregnancy. To the best of our knowledge, this is the first such case to be reported.Case Presentation: The mother conceived a dichorionic diamniotic twin pregnancy following clomiphene in...

Introduction: Short stature (SS) is one of the most common reasons for referral to a pediatric endocrinologist. SS is defined as a condition in which an individual's height is below the 3rd percentile for age and sex. SS may be caused by hormonal (eg. growth hormone deficiency), environmental (eg. intrauterine growth retardation) and genetic disorders (eg. Turner syndrome, Noonan syndrome). The evaluation of children presenting with SS comprises detailed ...