ESPE Abstracts

Background: Pelvic ultrasound is used for the diagnosis and follow-up of girls with precocious puberty (PP). This tool may be somewhat misleading, because during treatment some patients may persist with pubertal uterine and ovarian anatomy. Oestrogens decrease the resistance of the uterine arteries, so Doppler evaluation of these vessels might be a useful complementary exam to determine the effects of treatment in these patients.Objective and hypotheses:...

Patient 10 years old, female, since 8 years old of excessive weight gain, facial changes, hirsutism, violaceous striae on trunk, abdomen and legs, acanthosis nigricans, dorsal cervical fat pad, muscle weakness and sleep disturbances. Menarche at 9 years old. Weight 110.4 kg, height 141.6 cm (+0.08 SD), BMI 55.1 (+4.67 SD). Initial study HBA1C 5.17%, glycemia 86 mg/dl DHEAS110 ug/dl, Total testosterone 39.19 ng/dl, SHBG10nmol/l, FAI 3.09, Androstenedione 2.5 ng/ml, 17 hydroxipr...

Case presentation: We present the case of a 6-year-old female patient with history of congenital salt-wasting adrenal hyperplasia (CAH) under treatment with hydrocortisone and fludrocortisone, who during the study of her urogenital sinus shows bilateral medullary nephrocalcinosis (NC) in the urethrocystography. The patient was born with a disorder of sex development, with apparently male genitalia, with a phallus and labioscrotal folds. Her karyotype is 46XX, ...

We report three cases of patients with pancreatitis that developed diabetes mellitus (DM). Case 1: 8,9 years old female, treated with valproic acid (VPA) for epilepsy. Who is admitted with 5 days of abdominal pain, vomiting and altered state of consciousness, in the ER the patient was dehydrated and initial labs showed glycemia of 423 mg/dl. She was admitted to the ICU, further studiesResults: amylase 502 U/L, lipase 1491 U/L, HbA1c 5.4%...

Case presentation: We report two cases of patients with Cystic fibrosis-related diabetes (CFRD) Patient 1. At 5 years of age, a genetic diagnosis of cystic fibrosis with homozygous delta F508 variant was made in relation to a brother diagnosed in the newborn period. At 12 years old FEV1 91%. Initial screening at age 14 with impaired fasting glucosa and HbA1c of 5.9%; She was overweight and had acanthosis. Hospitalizations for recurrent pneumonia. At 17 years o...

Background: Severe obesity among adolescents is increasing worldwide. Bariatric surgery is a controversial subject in this group of age, surgical timing is even more controversial. Patterns of surgical weight loss could be different between patients with greater excess weight, perhaps with less promising results.Objective and hypotheses: To compare anthropometric outcomes among adolescents with BMI 35–40 and over 40, underwent laparoscopic sleeve ga...