hrp0086p2-p942 | Thyroid P2 | ESPE2016

Euthyroid Hashimoto Thyroiditis in Children: Evolution Over Time

Karachaliou Feneli , Kafetzi Maria , Vlachopapadopoulou Elpis , Thomas Dimitris , Kaloumenou Irene , Fotinou Aspasia , Karavanaki Kyriaki , Michalakos Stefanos

Background: The natural evolution of euthyroid Hashimoto thyroiditis (HT) varies among children and treatment in children with HT and normal/mild elevated serum TSH is controversial.Objective and hypotheses: The aim was to study the natural course of HT in children and evaluate predictive factors of thyroid functionMethod: We evaluated data from 87 children retrospectively (63 girls, 24 boys), mean age 10.6±3.2yrs, with HT [an...

hrp0082p2-d2-473 | Growth (1) | ESPE2014

GH Deficiency in a Child With De Novo 2q31.1 Microdeletion

Kaloumenou Irene , Karachaliou Feneli , Vlachopapadopoulou Elpis-Athina , Fotinou Aspasia , Michalacos Stefanos

Background: The clinical phenotype of the chromosome 2q31 deletion syndrome consists of a variety of limb abnormalities and other skeletal defects, craniofacial dysmorhic features, developmental delay, and other not specific congenital anomalies.Objective and hypotheses: To describe a patient with 2q31.1 microdeletion syndrome and short stature, diagnosed with GH deficiency.Method: We describe a 5 years and 4 months girl with devel...

hrp0082p3-d3-793 | Fat Metabolism & Obesity (2) | ESPE2014

Prevalence of Abnormalities of Glucose Metabolism in Obese Greek Children and Adolescents

Karachaliou Feneli , Kaloumenou Irene , Vlachopapadopoulou Elpis-Athina , Katsixti Paraskeui , Fotinou Aspasia , Michalacos Stefanos

Background: Obesity is associated with alterations in glucose metabolism, often present from childhood.Objective and hypotheses: To assess the prevalence of glucose metabolism alterations and insulin resistance in a group of obese, otherwise healthy children and adolescents from Greece.Method: It is a retrospective study of 130 obese children and adolescents, 79 girls (61%), aged 5.4 to 15.2 years (mean±S.D.: 10...

hrp0086p1-p33 | Adrenal P1 | ESPE2016

Usefulness of Corticotropin Test in Children and Adolescents with Clinical Hyperandrogenism

Karachaliou Feneli , Kafetzi Maria , Vlachopapadopoulou Elpis , Drakopoulou Maria , Kaloumenou Irene , Kapella Antonia , Fotinou Aspasia , Psina Antonia , Michalakos Stefanos

Background: The usefulness of corticotrophin (ACTH) test in diagnosis of 21-hydroxylase deficiency and/or other enzymic defects in children and adolescents with serum levels of 17-OHP (before 2000 h) >2 ng/ml is known.Objective and hypotheses: To evaluate the usefulness of ACTH test in diagnosis of non-classical congenital adrenal hyperplasia (NCCAH) and heterozygosity of CYP21 gene molecular defects in children and adolescents with clinical hyperand...