hrp0092p1-204 | Fetal, Neonatal Endocrinology and Metabolism (to include Hypoglycaemia) (1) | ESPE2019

Risk Factors for Brain Injury After Transient or Persistent Hyperinsulinemic Hypoglycemia in Neonates

Roeper Marcia , Dafsari Roschan Salimi , Kummer Sebastian , Klee Dirk , Mayatepek Ertan , Sabir Hemmen , Meissner Thomas

Background: Aim of this study was to identify possible explanations why despite improved treatment options brain damage still occurs in neonates with transient or persistent hyperinsulinism. This study might serve as a basis for future research to improve the management of neonatal hypoglycemia reducing brain injury in these children.Material and Methods: A retrospective medical chart review was conducted at the Universi...

hrp0086p1-p210 | Diabetes P1 | ESPE2016

Screening for Liver Disease in Children and Adolescents with Type 1 Diabetes Mellitus: A Cross-sectional Analysis

Kummer Sebastian , Klee Dirk , Kircheis Gerald , Friedt Michael , Schaper Joerg , Haussinger Dieter , Mayatepek Ertan , Meissner Thomas

Background: The liver is one of the most important organs in glucose metabolism and closely related to diabetes pathophysiology. Non-alcoholic fatty liver disease (NAFLD) is well known in type 2 diabetes mellitus (DM), but also adult patients with type 1 DM are at increased risk for NAFLD.Objective and hypotheses: Here, we studied the prevalence of liver disease in a representative number of children and adolescents with type 1 DM in Germany.<p class...