hrp0084p1-7 | Adrenal | ESPE2015

Carriers of 21-Hydroxylase Deficiency Demonstrate Increased Psychological Vulnerability to Stress

Koltsida Georgia , Farakla Ioanna , Papanikolaou Aikaterini , Kolaitis Gerasimos , Mantzou Emilia , Charmandari Evangelia

Background: Carriers of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21-OHD) demonstrate increased secretion of cortisol precursors following ACTH stimulation, suggestive of impaired cortisol production, and compensatory increases in hypothalamic CRH secretion. Both cortisol and CRH have behavioural effects, and hypothalamic CRH hypersecretion has been associated with chronic states of anxiety and depression.Objective and hypoth...

hrp0097p1-460 | Fat, Metabolism and Obesity | ESPE2023

Improvement of Depressive and Anxiety Symptoms in Children and Adolescents with Overweight and Obesity Following Implementation of a Comprehensive, Multidisciplinary, Personalized, Lifestyle Intervention Program

Vourdoumpa Aikaterini , Paltoglou George , Kassari Penio , Manou Maria , Papadopoulou Marina , Kolaitis Gerasimos , Charmandari Evangelia

Introduction: Childhood obesity is one of the most challenging contemporary public health problems. Children and adolescents with obesity experience multiple psychosocial difficulties, such as low self-esteem, depression, anxiety, and behavioral problems. Psychosocial problems noted in youngsters with excess adiposity persist for a long time. The aim of our study was to assess mental health symptoms in overweight and obese children and adolescents before and a...

hrp0089p3-p149 | Fat, Metabolism and Obesity P3 | ESPE2018

The Effect of Vitamin D Supplementation on Metabolic Syndrome Parameters in Overweight and Obese Children and Adolescents in Greece

Giannios Christos , Nicolaides Nicolas , Farakla Ioanna , Papadopoulos Georgios , Gennitsaridi Sofia , Karampatsou Sofia , Kolaitis Gerasimos , Chrousos George , Charmandari Evangelia

Background: Accumulating evidence suggests that decreased 25-hydroxyvitamin [25(OH)D] concentrations are associated with components of the metabolic syndrome.Objective: The aim of our study was to investigate the effect of vitamin D supplementation on metabolic syndrome parameters in obese children and adolescents.Patients and methods: Two hundred thirty two (n=232) obese children and adolescents aged [mean ±S....