hrp0097p1-258 | Fat, Metabolism and Obesity | ESPE2023
Karabouta Zacharoula
, Simeoforidou Elpida
, Georgoulia Konstandina
, Koniari Eleni
, Bisbinas Alexia
, Chrousos George
Introduction: Familial hypercholesterolaemia(FH) is a genetic disorder affecting approximately 1 in 250 people, resulting in high levels of low-density lipoprotein Cholesterol(LDL-C), increasing the likelihood of developing cardiovascular disease(CVD) at a younger age. Lipoprotein (a)(Lp(a)) is another risk factor for atherosclerosis, elevated in 20-25% of people and 90% genetically determined, only slightly reduced by diet, exercise and medication.<p clas...