hrp0082fc13.5 | Thyroid | ESPE2014

The Ultrastructural Changes in Thyroid Cells in the Course of Damage in Hashimoto’s Thyroiditis

Ben-Skowronek Iwona , Szewczyk Leszek , Korobowicz Elzbieta

Background: The development of the Hashimoto’s thyroiditis is the result of the damage to thyrocytes, apoptosis, and autoimmune cytotoxic action of lymphocytes.Objective and Hypotheses: The aim of the study is to present ultrastructural changes in thyroid cells in the course of damage in Hashimoto’s thyroiditis.Method: The study involved 40 children: 20 children with Hashimoto’s thyroiditis and 20 children as a contr...

hrp0082p3-d1-978 | Thyroid | ESPE2014

Treatment the Resistance to Thyroid Hormones in Girl

Budzynska Elzbieta , Ben-Skowronek Iwona , Korobowicz Elzbieta , Klatka Maria

Background: The cardinal feature of the resistance to thyroid hormone (RTH) is reduced responsiveness of target tissues to thyroid hormone action caused by thyroid hormone receptor β gene (THRB) mutations impairing hormone binding in the majority (90%) of cases. It results in elevated serum levels of free thyroxine (FT4) and triiodothyronine (FT3) associated with unsuppressed thyroid SH.Objective and hypotheses: The ai...